# Case Report: Bone fragment in the third ventricle of a 22 year-old woman

**Authors:** Sunil Munakomi, Balaji Srinivas, Iype Cherian, Andrey Belkin, Alexey Pychteev

PMC · DOI: 10.12688/f1000research.6180.1 · F1000Research · 2015-03-11

## TL;DR

A 22-year-old woman had a rare bone fragment in her brain's third ventricle after a severe head injury from a traffic accident.

## Contribution

This case report adds to the limited literature on foreign objects in the third ventricle and their clinical outcomes.

## Key findings

- A bone fragment was found in the third ventricle following a compound-depressed skull fracture.
- The patient required hormone replacement therapy after surgical removal of the fragment.
- The patient ultimately died due to severe traumatic hypothalamic injury.

## Abstract

Here we present a very rare case of a woman with a bone fragment in the third ventricle of the brain following compound-depressed skull fractures due to a road traffic accident.

There are only few case reports of bullets and textiloma being removed from the third ventricle. Following operative removal of the fragment, the patient was started on cortisol, mineralocorticoid and thyroid hormone replacement. However, the patient eventually died of the severe traumatic hypothalamic insult.

## Linked entities

- **Chemicals:** cortisol (PubChem CID 5754)

## Full-text entities

- **Diseases:** brain abscesses (MESH:D001922), elevated intracranial pressure (MESH:D019586), trauma (MESH:D014947), craniocerebral injuries (MESH:D006259), depressed (MESH:D003866), Glasgow coma (MESH:D003128), cerebrospinal fluid fistula (MESH:D002559), blunt trauma (MESH:D014949), hematoma (MESH:D006406), hypotension (MESH:D007022), Bone fragment in (MESH:D012892), hemorrhages (MESH:D006470), seizures (MESH:D012640), infection (MESH:D007239), road traffic accident (MESH:D000081084), textiloma (MESH:D005547), diencephalic syndrome (MESH:D007027), depressed fracture (MESH:D020204), ventricle of the brain (MESH:D001927), hydrocephalus (MESH:D006849), brain tissue damage (MESH:D017695), ventriculitis (MESH:D058565), meningitis (MESH:D008580), tetanus (MESH:D013746)
- **Chemicals:** fludrocortisone (MESH:D005438), cortisol (MESH:D006854)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4560254/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC4560254/full.md

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Source: https://tomesphere.com/paper/PMC4560254