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Taxonomy
TopicsParasitic infections in humans and animals · Congenital Anomalies and Fetal Surgery · Travel-related health issues
Dear Sir:
We appreciate the response to our article “Intraventricular Taenia solium Cysts Presenting with Bruns Syndrome and Indications for Emergent Neurosurgery.” The concern for underreporting the positional symptoms of ventricular cysticercosis as Bruns syndrome is noted, but our search criteria included the term “Bruns” and these other reports did not use that eponym. More importantly, the primary scope of our article was to increase awareness and management for severe cases of intraventricular neurocysticercosis.
Considering enzyme-linked immunosorbent assays (ELISAs), we stated that serological analysis has an adjunct role and that treatment should not be delayed for pending serological studies. Although imaging is the preferred modality for diagnosis, it is not 100% reliable in distinguishing cysticercosis from other neurological masses.1 Also, a positive ELISA can provide epidemiologic information for a possible source of infection, as in classic studies from New York City, NY.2,3
Regarding treatment with anthelmintics before surgery, the data are limited. We did not stress the need for albendazole before surgery, and only one of the two cases received prior treatment. In fact, we stated that medical management should be avoided for patients presenting with neurological emergency. Considering antiparasitic drugs after surgery, it has been reported that small cysts, not removed by surgery, can be missed by magnetic resonance imaging and cause further complications in an already tenuous post-neurosurgical patient.4 It has also been reported that postsurgery antiparasitics may help in preventing shunt failures.5 Although imaging modalities have greatly improved in resource-rich countries, these may be unavailable in resource-limited areas.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Del Brutto OH Rajshekhar V White AC Jr Tsang VC Nash TE Takayanagui OM Schantz PM Evans CA Flisser A Correa D Botero D Allan JC Sarti E Gonzalez AE Gilman RH García HH 2001 Proposed diagnostic criteria for neurocysticercosis Neurology 571771831148042410.1212/wnl.57.2.177PMC 2912527 · doi ↗ · pubmed ↗
- 2Schantz PM Moore AC Muñoz JL Hartman BJ Schaefer JA Aron AM Persaud D Sarti E Wilson M Flisser A 1992 Neurocysticercosis in an Orthodox Jewish community in New York City N Engl J Med 327692695149552110.1056/NEJM 199209033271004 · doi ↗ · pubmed ↗
- 3Moore AC Lutwick LI Schantz PM Pilcher JB Wilson M Hightower AW Chapnick EK Abter EI Grossman JR Fried JA Ware DA Haichou X Hyon SS Barbour RL Antar R Hakim A 1995 Seroprevalence of cysticercosis in an Orthodox Jewish community Am J Trop Med Hyg 53439442748570010.4269/ajtmh.1995.53.439 · doi ↗ · pubmed ↗
- 4Mejia R Nash T 2013 Corticosteroids withdrawal precipitates perilesional edema around calcified Taenia solium cysts Am J Trop Med Hyg 899199232400248210.4269/ajtmh.13-0350 PMC 3820336 · doi ↗ · pubmed ↗
- 5Gongora-Rivera F Soto-Hernandez JL Gonzalez Esquivel D Cook HJ Marquez-Caraveo C Hernandez Davila R Santos-Zambrano J 2006 Albendazole trial at 15 or 30 mg/kg/day for subarachnoid and intraventricular cysticercosis Neurology 664364381638203510.1212/01.wnl.0000195887.63124.dc · doi ↗ · pubmed ↗
