# 3D Rapid Prototyping for Otolaryngology—Head and Neck Surgery: Applications in Image-Guidance, Surgical Simulation and Patient-Specific Modeling

**Authors:** Harley H. L. Chan, Jeffrey H. Siewerdsen, Allan Vescan, Michael J. Daly, Eitan Prisman, Jonathan C. Irish

PMC · DOI: 10.1371/journal.pone.0136370 · PLoS ONE · 2015-09-02

## TL;DR

This study explores how 3D rapid prototyping can be used in head and neck surgery for training, simulation, and patient-specific modeling.

## Contribution

The paper introduces three novel applications of rapid prototyping in otolaryngology surgery: training phantoms and patient-specific models.

## Key findings

- Phantom models received positive feedback for realism but need improvements in soft tissue structure.
- Pre-operative plates using 3D models showed good conformance in 7 out of 10 cases.
- Rapid prototyping reduces operating room time without affecting plate fabrication time or conformance.

## Abstract

The aim of this study was to demonstrate the role of advanced fabrication technology across a broad spectrum of head and neck surgical procedures, including applications in endoscopic sinus surgery, skull base surgery, and maxillofacial reconstruction. The initial case studies demonstrated three applications of rapid prototyping technology are in head and neck surgery: i) a mono-material paranasal sinus phantom for endoscopy training ii) a multi-material skull base simulator and iii) 3D patient-specific mandible templates. Digital processing of these phantoms is based on real patient or cadaveric 3D images such as CT or MRI data. Three endoscopic sinus surgeons examined the realism of the endoscopist training phantom. One experienced endoscopic skull base surgeon conducted advanced sinus procedures on the high-fidelity multi-material skull base simulator. Ten patients participated in a prospective clinical study examining patient-specific modeling for mandibular reconstructive surgery. Qualitative feedback to assess the realism of the endoscopy training phantom and high-fidelity multi-material phantom was acquired. Conformance comparisons using assessments from the blinded reconstructive surgeons measured the geometric performance between intra-operative and pre-operative reconstruction mandible plates. Both the endoscopy training phantom and the high-fidelity multi-material phantom received positive feedback on the realistic structure of the phantom models. Results suggested further improvement on the soft tissue structure of the phantom models is necessary. In the patient-specific mandible template study, the pre-operative plates were judged by two blinded surgeons as providing optimal conformance in 7 out of 10 cases. No statistical differences were found in plate fabrication time and conformance, with pre-operative plating providing the advantage of reducing time spent in the operation room. The applicability of common model design and fabrication techniques across a variety of otolaryngological sub-specialties suggests an emerging role for rapid prototyping technology in surgical education, procedure simulation, and clinical practice.

## Full-text entities

- **Diseases:** mandible fracture (MESH:C563485), bone fractures (MESH:D050723), pituitary tumors (MESH:D010911), osteoradionecrosis (MESH:D010025), neoplastic (MESH:D009369), ESS (MESH:D012852), swelling (MESH:D004487), ameloblastoma (MESH:D000564), Head and Neck (MESH:D006258), inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606], Dipturus trachyderma (ray, species) [taxon 255564]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4557980/full.md

## References

57 references — full list in the complete paper: https://tomesphere.com/paper/PMC4557980/full.md

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Source: https://tomesphere.com/paper/PMC4557980