# Acute renal allograft dysfunction due to cecal volvulus: a case report

**Authors:** Sherry-Ann N. Brown, Patrick G. Dean, LaTonya J. Hickson

PMC · DOI: 10.1186/s40064-015-1229-7 · SpringerPlus · 2015-08-22

## TL;DR

A kidney transplant patient experienced acute kidney injury due to a rare condition called cecal volvulus, which compressed the allograft ureter.

## Contribution

This is the first reported case linking cecal volvulus directly to acute kidney injury in a kidney transplant recipient.

## Key findings

- Acute kidney injury in the patient was caused by external compression of the allograft ureter due to cecal volvulus.
- Surgical intervention resolved the obstruction and improved kidney function.
- Cecal volvulus should be considered in the differential diagnosis for acute kidney injury in transplant patients.

## Abstract

Among kidney transplant recipients with acute kidney injury, the differential diagnosis must be broadened to include conditions such as rejection, immunocompromised host infections, anatomic pathologies, and recurrent or de novo glomerular diseases. In this case report, we describe an unusual cause of acute renal allograft injury due to external compression of the allograft ureter.

Retrospective review; case report.

The patient developed acute kidney injury of the renal allograft due to external compression of the allograft ureter coincident with a cecal volvulus. The patient underwent lysis of adhesions, right hemicolectomy, and end ileostomy creation with resolution of acute kidney injury.

Cecal volvulus is an uncommon cause of bowel obstruction and is often associated with adhesions following abdominal surgery. To our knowledge, cecal volvulus has not previously been reported as a direct contributor to acute kidney injury. This case highlights the need for a systematic approach to the patient with acute kidney injury and the special considerations involved in the diagnosis of renal failure in the kidney transplant population.

## Linked entities

- **Diseases:** acute kidney injury (MONDO:0002492)

## Full-text entities

- **Diseases:** stricture (MESH:D003251), ischemia (MESH:D007511), metabolic acidemia (MESH:D008659), hypotension (MESH:D007022), associated (MESH:D018886), lupus nephritis (MESH:D008181), ischemic cardiomyopathy (MESH:D009202), tubular, interstitial, or glomerular injury (MESH:D017563), emesis (MESH:D014839), fibrosis (MESH:D005355), hematuria (MESH:D006417), Renal allograft complications (MESH:D007674), macrocytic anemia (MESH:D000748), adhesions (MESH:D000267), upper extremity tremors (MESH:D014202), Ureteral obstruction (MESH:D014517), nausea, vomiting (MESH:D020250), pyuria (MESH:D011776), constipation (MESH:D003248), AKI (MESH:D058186), toxicities (MESH:D064420), hydronephrosis (MESH:D006869), interstitial nephritis (MESH:D009395), interstitial inflammation (MESH:D007249), anatomic abnormalities (MESH:D020763), renal cell carcinoma (MESH:D002292), colonic distension (MESH:D003108), proteinuria (MESH:D011507), pyelonephritis (MESH:D011704), renal failure (MESH:D051437), fungal infections (MESH:D009181), ATN (MESH:D007683), thrombotic microangiopathy (MESH:D057049), gastrointestinal disturbances (MESH:D005767), diarrhea (MESH:D003967), ischemic injury (MESH:D017202), infections (MESH:D007239), glomerulonephritis (MESH:D005921), allograft dysfunction (MESH:D000092122), Cecal volvulus (MESH:D002429), tubular toxicity (MESH:D000230), abdominal discomfort (MESH:D000007), malrotation (MESH:C562456), bowel obstruction (MESH:D012778)
- **Chemicals:** Tacrolimus (MESH:D016559), Fluconazole (MESH:D015725), prednisone (MESH:D011241), mycophenolate mofetil (MESH:D009173), creatinine (MESH:D003404), Azole (MESH:D001393), bicarbonate (MESH:D001639)
- **Species:** Homo sapiens (human, species) [taxon 9606], Betapolyomavirus hominis (species) [taxon 1891762]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4546076/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC4546076/full.md

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Source: https://tomesphere.com/paper/PMC4546076