# LC/MS/MS data analysis of the human uterine smooth muscle S-nitrosoproteome fingerprint in pregnancy, labor, and preterm labor

## TL;DR

This study uses mass spectrometry to analyze protein modifications in uterine muscle during pregnancy, labor, and preterm labor.

## Contribution

The novel contribution is identifying S-nitrosoproteome differences in human uterine smooth muscle under various labor conditions.

## Key findings

- S-nitrosoproteome fingerprints differ between laboring and non-laboring uterine tissues.
- Preterm labor tissues show distinct S-nitrosoproteome profiles after S-nitrosoglutathione treatment.
- Mass spectrometry reveals large-scale changes in protein nitrosylation during labor states.

## Abstract

The data described in this article is the subject of an article in the American Journal of Physiology: Cell Physiology, titled “The Human Uterine Smooth Muscle S-nitrosoproteome Fingerprint in Pregnancy, Labor, and Preterm Labor” (doi:10.1152/ajpcell.00198.2013) (Ulrich et al., 2013) [1]. The data described is a large scale mass spectrometry data set that defines the human uterine smooth muscle S-nitrosoproteome differences among laboring, non-laboring, preterm laboring tissue after treatment with S-nitrosoglutathione.