# Management of a Gastrobronchial Fistula Connected to the Skin in a Giant Extragastric Stromal Tumor

## TL;DR

A 47-year-old man with a large stomach tumor developed severe complications from imatinib treatment, which were successfully managed with surgery and gastroscopy.

## Contribution

The paper presents a rare case of a gastrobronchial fistula connected to the skin in a patient with a giant stromal tumor.

## Key findings

- Imatinib therapy can cause life-threatening complications such as massive gastrointestinal bleeding.
- A gastrobronchial fistula connected to the skin was successfully treated with surgery and gastroscopy.
- Creative strategies are needed to manage complications from imatinib therapy.

## Abstract

Introduction. Gastrointestinal stromal tumors first treatment should be surgical resection, but when metastases are diagnosed or the tumor is unresectable, imatinib must be the first option. This treatment could induce some serious complications difficult to resolve. Case Report. We present a 47-year-old black man with a giant unresectable gastric stromal tumor under imatinib therapy who presented serious complications such as massive gastrointestinal bleeding and a gastrobronchial fistula connected with the skin, successfully treated by surgery and gastroscopy. Discussion. Complications due to imatinib therapy can result in life threatening. They represent a challenge for surgeons and digestologists; creative strategies are needed in order to resolve them.