# Fever Through a Jaundiced Eye

**Authors:** Christina C. Kennelly, Chelsey A. Petz, Don C. Rockey

PMC · DOI: 10.1177/2324709614533513 · 2014-04-29

## TL;DR

Pyogenic liver abscess is a treatable cause of fever and abdominal pain, especially in patients with biliary tract issues.

## Contribution

Highlights the importance of imaging and percutaneous drainage in diagnosing and managing pyogenic liver abscess.

## Key findings

- Imaging techniques have made diagnosing pyogenic liver abscess more straightforward.
- Percutaneous drainage has revolutionized the treatment of the condition.
- PLA should be considered in patients with biliary tract disease.

## Abstract

Pyogenic liver abscess (PLA) is an important clinical entity to consider in a patient with fever and abdominal pain. Previously, the condition was difficult to diagnose and treat, but with the introduction of widely available and reliable imaging techniques, its diagnosis has become more straightforward. Although uncommon, PLA should especially be considered in the differential diagnosis for patients with specific predisposing conditions such as underlying biliary tract disease, whether as a result of chronic inflammatory disease or malignancy. The introduction of percutaneous drainage has revolutionized the management of PLA, and thus, this disease has become largely correctable.

## Full-text entities

- **Genes:** TF (transferrin) [NCBI Gene 7018] {aka HEL-S-71p, PRO1557, PRO2086, TFQTL1}, HP (haptoglobin) [NCBI Gene 3240] {aka HP2ALPHA2, HPA1S}
- **Diseases:** appendicitis (MESH:D001064), melena (MESH:D008551), pharyngitis (MESH:D010612), hypertension (MESH:D006973), sweats (MESH:D013543), erythema (MESH:D004890), PSC (MESH:D015209), hematemesis (MESH:D006396), chills (MESH:D023341), inflammatory bowel disease (MESH:D015212), abdominal trauma (MESH:D000007), fatigue (MESH:D005221), infection (MESH:D007239), AMA (MESH:D008101), Fever (MESH:D005334), abdominal pain (MESH:D015746), gallstone disease (MESH:D002769), amebic (MESH:D000562), hepatosplenomegaly (MESH:C535727), cholangiocarcinoma (MESH:D018281), chronic inflammatory disease (MESH:D002908), PLA (MESH:D046290), dyspnea (MESH:D004417), chest pain (MESH:D002637), intra-abdominal infections (MESH:D059413), liver abscess (MESH:D008100), weight loss (MESH:D015431), cholangitis (MESH:D002761), abscess (MESH:D000038), malignancy (MESH:D009369), vomiting (MESH:D014839), nausea (MESH:D009325), anorexia (MESH:D000855), low back pain (MESH:D017116), colonic inflammation (MESH:D007249), cough (MESH:D003371), icterus (MESH:D007565), biliary disease (MESH:D001660), colitis (MESH:D003092), hemorrhoid (MESH:D006484)
- **Chemicals:** alcohol (MESH:D000438), ibuprofens (MESH:D007052), oxygen (MESH:D010100), metronidazole (MESH:D008795), ferrous sulfate (MESH:C020748), ceftriaxone (MESH:D002443), bilirubin (MESH:D001663), cetirizine (MESH:D017332), hydrochlorothiazide (MESH:D006852), iron (MESH:D007501), levofloxacin (MESH:D064704), vitamin B12 (MESH:D014805), amoxicillin (MESH:D000658), piperacillin/tazobactam (MESH:D000077725), vancomycin (MESH:D014640), azithromycin (MESH:D017963), valsartan (MESH:D000068756), fluticasone (MESH:D000068298), vitamin C (MESH:D001205)
- **Species:** Klebsiella (genus) [taxon 570], Nicotiana tabacum (American tobacco, species) [taxon 4097], Homo sapiens (human, species) [taxon 9606], Streptococcus milleri (species) [taxon 33040], Escherichia coli (E. coli, species) [taxon 562]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4528887/full.md

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Source: https://tomesphere.com/paper/PMC4528887