# Comparison of Infectious Agents Susceptibility to Photocatalytic Effects of Nanosized Titanium and Zinc Oxides: A Practical Approach

**Authors:** Janusz Bogdan, Joanna Zarzyńska, Joanna Pławińska-Czarnak

PMC · DOI: 10.1186/s11671-015-1023-z · Nanoscale Research Letters · 2015-08-04

## TL;DR

This paper compares how well nanosized titanium and zinc oxides can kill different types of infectious agents using photocatalytic processes.

## Contribution

The study provides a practical comparison of the susceptibility of various infectious agents to TiO2 and ZnO photocatalytic disinfection.

## Key findings

- Photocatalytic processes using TiO2 and ZnO are highly efficient in inactivating infectious agents.
- The susceptibility of pathogens to photocatalytic disinfection follows a specific order: viruses are most susceptible, followed by prions, Gram-negative bacteria, Gram-positive bacteria, yeasts, and molds.

## Abstract

Nanotechnology contributes towards a more effective eradication of pathogens that have emerged in hospitals, veterinary clinics, and food processing plants and that are resistant to traditional drugs or disinfectants. Since new methods of pathogens eradication must be invented and implemented, nanotechnology seems to have become the response to that acute need. A remarkable achievement in this field of science was the creation of self-disinfecting surfaces that base on advanced oxidation processes (AOPs). Thus, the phenomenon of photocatalysis was practically applied. Among the AOPs that have been most studied in respect of their ability to eradicate viruses, prions, bacteria, yeasts, and molds, there are the processes of TiO2/UV and ZnO/UV. Titanium dioxide (TiO2) and zinc oxide (ZnO) act as photocatalysts, after they have been powdered to nanoparticles. Ultraviolet (UV) radiation is an agent that determines their excitation. Methods using photocatalytic properties of nanosized TiO2 and ZnO prove to be highly efficient in inactivation of infectious agents. Therefore, they are being applied on a growing scale. AOP-based disinfection is regarded as a very promising tool that might help overcome problems in food hygiene and public health protection. The susceptibility of infectious agents to photocatalylic processes can be generally arranged in the following order: viruses > prions > Gram-negative bacteria > Gram-positive bacteria > yeasts > molds.

## Linked entities

- **Chemicals:** TiO2 (PubChem CID 26042), ZnO (PubChem CID 14806)

## Full-text entities

- **Diseases:** rubella (MESH:D012409), Sjogren (MESH:D012859), infection (MESH:D007239), SARS (MESH:D045169), respiratory tract infections (MESH:D012141), Prion (MESH:D017096), food poisonings (MESH:D005517), Allergies (MESH:D004342), smallpox (MESH:D012899), mumps (MESH:D009107), VRE (MESH:D060467), infectious (MESH:D003141), influenza (MESH:D007251), scrapie prion protein (MESH:D012608), Viruses Inactivation (MESH:C572568), sick building syndrome (MESH:D018877), DNA injury (MESH:D004266), measles (MESH:D008457), bacterial diseases (MESH:D001424), air-borne virus diseases (MESH:D014777), asthma (MESH:D001249)
- **Species:** Enterobacter cloacae (species) [taxon 550], Legionella pneumophila (species) [taxon 446], Fusarium oxysporum (species) [taxon 5507], Lactobacillus helveticus (species) [taxon 1587], Acinetobacter baumannii (species) [taxon 470], Hepatitis B virus (no rank) [taxon 10407], Vibrio cholerae (species) [taxon 666], Streptococcus pneumoniae (species) [taxon 1313], Severe acute respiratory syndrome-related coronavirus (no rank) [taxon 694009], Pseudomonas aeruginosa (species) [taxon 287], Bacillus subtilis (species) [taxon 1423], Aspergillus niger (species) [taxon 5061], Serratia marcescens (species) [taxon 615], Enterovirus C (no rank) [taxon 138950], Lacticaseibacillus casei (species) [taxon 1582], Bacillus pumilus (species) [taxon 1408], Staphylococcus epidermidis (species) [taxon 1282], Salmonella enterica subsp. enterica serovar Typhimurium (no rank) [taxon 90371], Bacillus anthracis (anthrax bacterium, species) [taxon 1392], Streptococcus pyogenes (species) [taxon 1314], Penicillium expansum (species) [taxon 27334], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Clostridium perfringens (species) [taxon 1502], Enterococcus faecium (species) [taxon 1352], Staphylococcus aureus (species) [taxon 1280], Candida albicans (species) [taxon 5476], Listeria monocytogenes (species) [taxon 1639], Escherichia coli (E. coli, species) [taxon 562], Viruses (acellular root) [taxon 10239], Campylobacter jejuni (species) [taxon 197], Enterococcus faecalis (species) [taxon 1351], Cupriavidus metallidurans (species) [taxon 119219], Feline calicivirus (no rank) [taxon 11978], Salmonella enterica subsp. enterica serovar Enteritidis (no rank) [taxon 149539], Klebsiella pneumoniae (species) [taxon 573], Lactobacillus acidophilus (species) [taxon 1579], Bacillus cereus (species) [taxon 1396], Saccharomyces cerevisiae (baker's yeast, species) [taxon 4932], Rotavirus A (no rank) [taxon 28875], Homo sapiens (human, species) [taxon 9606], Enterococcus sp. (species) [taxon 35783], Human alphaherpesvirus 1 (Herpes simplex virus type 1, no rank) [taxon 10298]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC4523504/full.md

## References

192 references — full list in the complete paper: https://tomesphere.com/paper/PMC4523504/full.md

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Source: https://tomesphere.com/paper/PMC4523504