# Data in support of global role of the membrane protease LonB in Archaea: Potential protease targets revealed by quantitative proteome analysis of a lonB mutant in Haloferax volcanii

## TL;DR

This study explores the role of the LonB protease in archaea by analyzing proteome changes in a mutant strain of Haloferax volcanii.

## Contribution

The first proteome analysis of a LonB-deficient archaeal cell, revealing potential protease targets.

## Key findings

- LonB protease influences proteome composition in Haloferax volcanii.
- Membrane and cytosol fractions showed distinct proteomic changes in the mutant.
- Quantitative analysis identified potential LonB protease targets in archaea.

## Abstract

This data article provides information in support of the research article “Global role of the membrane protease LonB in Archaea: Potential protease targets revealed by quantitative proteome analysis of a lonB mutant in Haloferax volcanii” [1]. The proteome composition of a wt and a LonB protease mutant strain (suboptimal expression) in the archaeon Haloferax volcanii was assessed by a quantitative shotgun proteomic approach. Membrane and cytosol fractions of H. volcanii strains were examined at two different growth stages (exponential and stationary phase). Data is supplied in the present article. This study represents the first proteome examination of a Lon-deficient cell of the Archaea Domain.