# Diagnostic accuracy of Pluslife MiniDock MTB on tongue swabs in sputum scarce people with presumptive TB: a retrospective analysis

**Authors:** Loren Rockman, Shima Abdulgader, Stephanie Minnies, Daphne Naidoo, Arthur Chiwaya, Welile Nwamba, Anna Okunola, Grant Theron

PMC · DOI: 10.21203/rs.3.rs-6225528/v1 · Research Square · 2026-03-23

## TL;DR

This study evaluates a new TB test using tongue swabs for people who cannot produce sputum, showing improved detection rates compared to traditional sputum tests.

## Contribution

The study introduces the use of tongue swabs with the MiniDock MTB test for diagnosing TB in sputum-scarce populations.

## Key findings

- The MiniDock MTB test detected 53% of tuberculosis cases in sputum-scarce individuals.
- Using tongue swabs halved the number of missed TB cases compared to relying on sputum tests alone.

## Abstract

MiniDock MTB (Pluslife, China) is a near-point-of-care swab-based tuberculosis test. Most data are from people who can expectorate sputum. In 86 sputum-scarce symptomatic adults, retrospective testing detected 53% (95% CI 28–77) of tuberculosis; halving the amount missed if only sputum tests were available.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** tuberculosis (MESH:D014376), TB (MESH:D014390)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13042174/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC13042174/full.md

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Source: https://tomesphere.com/paper/PMC13042174