# Two vs. Three Incisions for Hypoglossal Nerve Stimulator Implantation to Treat Sleep Apnea: A Systematic Review

**Authors:** Amanda Kettman, Annah M Smelley, Samantha Main, Rahul Garg

PMC · DOI: 10.7759/cureus.104514 · Cureus · 2026-03-01

## TL;DR

This paper compares two surgical techniques for implanting a sleep apnea treatment device, finding that the newer two-incision method is faster and has fewer follow-up surgeries.

## Contribution

The study provides a systematic review comparing two vs. three incision techniques for HNS implantation in sleep apnea treatment.

## Key findings

- The two-incision approach reduced operative time compared to the three-incision method.
- Fewer follow-up corrective surgeries were observed in the two-incision group.
- Sleep quality improved similarly in both techniques without significant differences.

## Abstract

Obstructive sleep apnea (OSA) is common among adults in the United States. Hypoglossal nerve stimulation (HNS) is a novel surgical alternative for OSA patients who are nonadherent to first-line treatments. Our systematic review evaluated the surgical and device outcomes of the traditional three-incision versus the newer, less-invasive two-incision HNS implantation technique. Four studies were included based on the inclusion and exclusion criteria. Two studies demonstrated a significant reduction in operative time from three-incision to two-incision (128.7 to 86.6 minutes and 143.3 to 129.4 minutes, respectively). Two studies reported better sleep waveform quality and non-inferior sleep quality index scores, and one study showed fewer follow-up corrective surgeries with the two-incision group (0% vs. 5.4%; p=0.048). Across most studies, postoperative complications were low. The sleep quality improved with both techniques without statistical significance. Based on limited evidence from observational studies, the two-incision approach shortened operative time and had fewer corrective follow-up surgeries without compromising sleep quality relative to the three-incision technique.

## Linked entities

- **Diseases:** Obstructive sleep apnea (MONDO:0007147), sleep apnea (MONDO:0005296)

## Full-text entities

- **Diseases:** OSA (MESH:D020181), Sleep Apnea (MESH:D012891)
- **Chemicals:** Hypoglossal (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13039217/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13039217/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC13039217/full.md

---
Source: https://tomesphere.com/paper/PMC13039217