# Social support and quality of life in patients with chronic liver disease: a mediating role of illness perception

**Authors:** Qin Xie, Tian Ren, Teng Li, Jia Liu, Wanni Yu, Xiaoling Fu, Dongmei Li, Li Liu, Mei Yang

PMC · DOI: 10.3389/fpsyg.2026.1613767 · Frontiers in Psychology · 2026-03-18

## TL;DR

This study shows that how patients perceive their illness affects how social support improves their quality of life in chronic liver disease.

## Contribution

It identifies illness perception as a complete mediator between social support and quality of life in chronic liver disease patients.

## Key findings

- Quality of life was positively linked to social support and negatively linked to illness perception.
- Illness perception fully mediated the relationship between social support and quality of life.
- Patients with better illness perception had higher quality of life despite lower social support.

## Abstract

Chronic liver disease is a major global health threat. With the progress of disease, patients will suffer from different complications, which seriously affect their quality of life. Social support and illness perception play key roles in improving quality of life. However, there is limited research on the relationship between social support, illness perception, and quality of life.

The STROBE guideline was performed in this study. 250 individuals in a Grade A hospital in China were selected by a convenience sampling approach. Data were collected by using a sociodemographic questionnaire, a Social Support Rating Scale, a Brief Illness Perception Questionnaire, and a 36-item Short Form Health Survey Questionnaire. IBM SPSS Amos 24.0 (IBM Corp.) and SPSS 26.0 (IBM Corp.) were used for data analysis.

The overall mean scores of social support, illness perception and quality of life were 26.538, 43.420 and 62.641, respectively. The quality of life was positively correlated with social support, while it was negatively related to illness perception. The social support was negatively correlated with illness perception. The illness perception acted as a mediator in the relationship between social support and quality of life.

Statistically, illness perception acts as a complete mediator in the association between social support and quality of life. Healthcare professionals should focus more on understanding and addressing patients’ illness perceptions to enhance their quality of life.

## Full-text entities

- **Diseases:** Chronic liver disease (MESH:D008107)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

37 references — full list in the complete paper: https://tomesphere.com/paper/PMC13039095/full.md

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Source: https://tomesphere.com/paper/PMC13039095