# Breast cancer pharmacotherapy and imaging interpretation: pathophysiological perspectives and clinical application

**Authors:** Roka Namoto Matsubayashi, Nobutaka Iwakuma

PMC · DOI: 10.1007/s11604-025-01926-y · Japanese Journal of Radiology · 2025-12-24

## TL;DR

This paper explores how drug treatments and imaging techniques work together to improve breast cancer care and patient outcomes.

## Contribution

The study highlights personalized treatment approaches based on cancer subtypes and imaging insights.

## Key findings

- Personalized treatments based on intrinsic subtypes improve outcomes.
- Imaging-guided decisions are crucial for optimizing therapy.
- Managing treatment-related adverse effects is emphasized.

## Abstract

Modern breast cancer treatment has evolved significantly, integrating advanced imaging techniques and a variety of drug therapies, including endocrine therapy, chemotherapy, molecularly targeted drugs, and immune checkpoint inhibitors. This study discusses the interplay of drug treatments and imaging diagnostics in optimizing patient outcomes. Key findings emphasize the importance of personalized treatments based on intrinsic subtypes and imaging-guided decisions, as well as the management of treatment-related adverse effects.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** Breast cancer (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13038685/full.md

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13038685/full.md

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Source: https://tomesphere.com/paper/PMC13038685