# Association study of the CSN2 gene with milk yield in the Sapera goat

## TL;DR

This study examines how a specific gene variant affects milk production in Sapera goats.

## Contribution

The study identifies a statistically significant SNP in the CSN2 gene influencing milk yield in Sapera goats.

## Key findings

- SNP g.8946C > T significantly affects milk yield (p < 0.05).
- Milk yield is influenced by parity and days in milk (p < 0.01).
- The CC genotype is associated with higher milk yield but lacks additive or dominance effects.

## Abstract

This research was conducted to assess the influence of CSN2 exon 7 milk production and the additive and dominance effects.

DNA was isolated from 64 goats that possessed the CSN2 gene and subjected to a polymerase chain reaction and genotyping by Sanger sequencing.Genotype effect can be assessed through analysis of variance and the generalized linear model, which can estimate additive and dominance effects.

Dairy traits are greatly influenced by the crucial role played by the CSN2 gene. The influence of SNP g.8946C > T on milk yield (MY) is statistically significant (p < 0.05). Nevertheless, the impact of SNP g.8956G > A on MY is not statistically significant. Furthermore, the MY of Sapera goats is affected by both Parity (p <0.01) and days in milk (p < 0.01).

The CC genotype demonstrates a higher MY without noticeable additive or dominance effects. Evaluating the SNP g.8946C > T necessitates many samples and phenotypes.