# Insights into bacterial stress adaptation, host interactions, and drug resistance: key findings from the fall 2025 ASM Theobald Smith Society meeting

**Authors:** Nitish Sharma, Madhulika Singh, Joycelyn Radeny, Arpita Mukherjee, Raymond F. Sullivan, Jeffrey M. Boyd, Valerie J. Carabetta, Jason H. Yang, Srujana S. Yadavalli

PMC · DOI: 10.1128/msphere.00878-25 · 2026-03-06

## TL;DR

This paper summarizes the research presented at a 2025 microbiology meeting focusing on bacteria's adaptation, host interactions, and drug resistance.

## Contribution

The paper compiles and highlights recent impactful discoveries from TSS members in the field of microbiology.

## Key findings

- The meeting featured 72 participants from diverse backgrounds presenting varied microbiology research.
- Key topics included bacterial stress adaptation and drug resistance mechanisms.
- The event showcased the breadth of research conducted by New Jersey-based microbiologists.

## Abstract

The annual fall meeting for the Theobald Smith Society (TSS), the New Jersey Branch of the American Society for Microbiology (ASM), took place in November 2025 at Cooper Medical School of Rowan University in Camden, New Jersey. A total of 72 branch members from across New Jersey participated, including undergraduate and graduate students, postdoctoral trainees, faculty, and professionals from government and industry. This report highlights the scope and diversity of research carried out by TSS members and celebrates their impactful discoveries.

## Full-text entities

- **Genes:** beta-lactamase [NCBI Gene 13913583], Catalase [NCBI Gene 28381092], indole-3-glycerol phosphate synthase [NCBI Gene 28381054], NADH dehydrogenase [NCBI Gene 28381518]
- **Diseases:** ASM DISTINGUISHED (MESH:C000719191), skin and soft tissue infections (MESH:D018461), PRESENTATION (MESH:D001946), MECHANISM DISCOVERY (MESH:D041781), TB (MESH:D014376), death (MESH:D003643), infection (MESH:D007239), respiratory infections (MESH:D012141), COVID-19 (MESH:D000086382), MDR (MESH:D018088), inflammatory (MESH:D007249), hypersensitivity (MESH:D004342), infectious diseases (MESH:D003141), MRSA (MESH:D013203), influenza (MESH:D007251), ENVIRONMENTAL (MESH:D018876), HEALTH (OMIM:603663)
- **Chemicals:** diarylquinoline (MESH:D064687), glycerol (MESH:D005990), tryptophan (MESH:D014364), glycan (MESH:D011134), lipid (MESH:D008055), trimethoprim (MESH:D014295), ethanol (MESH:D000431), ILV (MESH:C043969), oxygen (MESH:D010100), rifampicin (MESH:D012293), fatty acids (MESH:D005227), branched-chain amino acids (MESH:D000597), bedaquiline (MESH:C493870), Q (MESH:D005973), D2O (MESH:D017666), isoniazid (MESH:D007538), methicillin (MESH:D008712), BCFA (-), diglycine (MESH:D006033), ethambutol (MESH:D004977), ATP (MESH:D000255), valine (MESH:D014633), pyrazinamide (MESH:D011718), sphingolipid (MESH:D013107), leucine (MESH:D007930), GTP (MESH:D006160), menaquinone (MESH:D024482), queuosine (MESH:D009704), coenzyme A (MESH:D003065), magnesium (MESH:D008274), sulfonamides (MESH:D013449), ROS (MESH:D017382), folate (MESH:D005492), isoleucine (MESH:D007532)
- **Species:** Mycobacterium tuberculosis (species) [taxon 1773], Zymobacter (genus) [taxon 33073], Homo sapiens (human, species) [taxon 9606], Myrmecocystus mendax (species) [taxon 271140], gut metagenome (species) [taxon 749906], Thermotoga maritima (species) [taxon 2336], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Flavivirus [taxon 11051], Bos taurus (bovine, species) [taxon 9913], Staphylococcus aureus (species) [taxon 1280], Mycobacterium marinum (species) [taxon 1781], Bacteroides (genus) [taxon 816], Sus scrofa (pig, species) [taxon 9823], Escherichia coli (E. coli, species) [taxon 562], Bacillus subtilis (species) [taxon 1423], Vibrio (genus) [taxon 662], Mycobacterium leprae (species) [taxon 1769], Acetobacter subgen. Acetobacter (subgenus) [taxon 151157], Myrmecocystus (genus) [taxon 211520]
- **Mutations:** E47D, E157D

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13037399/full.md

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Source: https://tomesphere.com/paper/PMC13037399