# Oral dirofilariasis mimicking endodontic failure: a case report

**Authors:** Aleksandra Karkle, Ksenija Silina, Ilze Akota, Angelika Krumina, Anete Vaskevica, Katrina Gardovska, Laura Neimane, Anda Slaidina

PMC · DOI: 10.1186/s12903-026-08115-x · 2026-03-17

## TL;DR

A rare case of oral dirofilariasis was mistaken for a dental infection, highlighting the need for careful diagnosis and collaboration among specialists.

## Contribution

This case report adds to the limited literature on oral dirofilariasis mimicking dental abscesses and emphasizes diagnostic challenges.

## Key findings

- A live nematode was found in a periapical lesion initially thought to be an abscess.
- Histopathological analysis confirmed the presence of Dirofilaria spp.
- The patient recovered fully after endodontic retreatment.

## Abstract

Oral dirofilariasis is a rare parasitic infection that can mimic common dental pathologies. This report presents a unique case where dirofilariasis was mistaken for an acute apical abscess, highlighting diagnostic challenges and the importance of interdisciplinary collaboration.

A 47-year-old male presented with a persistent, painless swelling in the maxillary anterior region (tooth 11). Initial history and radiographic examinations suggested an acute apical abscess following inadequate root canal treatment. However, during surgical exploration, a live nematode was discovered in the periapical lesion. The parasite was extracted, and histopathological analysis confirmed Dirofilaria spp. The patient underwent endodontic retreatment and achieved full recovery.

This case underscores the need for clinicians to consider parasitic infections in atypical presentations of periapical pathology. Advanced imaging, thorough surgical assessment, and histopathological confirmation are essential in distinguishing rare infections from common dental diseases.

## Full-text entities

- **Diseases:** oral lesions (MESH:D009059), periapical defect (MESH:D010483), Dirofilaria infection (MESH:D007239), cysts (MESH:D003560), buccal swelling (MESH:D000080902), abscess (MESH:D000038), oral and facial swellings (MESH:D020820), bone (MESH:D001847), acute (MESH:D000208), pain (MESH:D010146), parasitic infection (MESH:D010272), acute apical abscess (MESH:D010482), Dirofilaria immitis (MESH:D003047), odontogenic lesions (MESH:D009808), zoonotic infections (MESH:D015047), neoplastic (MESH:D009369), apical (MESH:D010485), infectious disease (MESH:D003141), fever (MESH:D005334), Dirofilariasis (MESH:D004184), dental diseases (MESH:D009057), odontogenic infection (MESH:D018126), granulomas (MESH:D006099), facial swelling (MESH:D004487), worm infection (MESH:D017189), odontogenic conditions (MESH:D009807), inflammatory (MESH:D007249), endodontic failure (MESH:D051437)
- **Chemicals:** Calcium hydroxide (MESH:D002126), ethylenediaminetetraacetic acid (MESH:D004492), sodium hypochlorite (MESH:D012973), adrenaline (MESH:D004837)
- **Species:** Nematoda (nematode, phylum) [taxon 6231], Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615], Dirofilaria repens (species) [taxon 31241]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13037268/full.md

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Source: https://tomesphere.com/paper/PMC13037268