# Is neighborhood socioeconomic status associated with health behavior in Berlin? Cross-sectional data of the German National Cohort (NAKO)

**Authors:** Lilian Krist, Kathrin Wolf, Matthias B. Schulze, Tobias Pischon, Florian Herbolsheimer, Karen Steindorf, Thomas Keil

PMC · DOI: 10.1186/s12889-026-26734-5 · 2026-02-23

## TL;DR

This study explores how the socioeconomic status of neighborhoods in Berlin relates to healthy lifestyle behaviors using data from the German National Cohort.

## Contribution

The study provides new insights into the association between neighborhood socioeconomic status and health behaviors in a large urban population.

## Key findings

- Lower neighborhood socioeconomic status was linked to slightly worse healthy lifestyle scores.
- Stronger associations were found with BMI and smoking, but not with alcohol consumption or physical activity.
- Differences were mainly driven by the most disadvantaged neighborhoods compared to others.

## Abstract

Neighborhood socioeconomic status (nSES) can complement individual SES to better assess health-behavior inequalities. The aim of this study was to investigate the relationship between the nSES of defined areas in Berlin with healthy lifestyle.

This cross-sectional analysis used baseline data from the three Berlin study centers of the German National Cohort (NAKO). We assessed body mass index (BMI), smoking, alcohol consumption, and objectively measured physical activity and combined them to a healthy lifestyle index (HLI; range:0–12 points; 12 = best score). To assess nSES, the Social Index from Berlin’s Social Structure Atlas (1 = best; 7 = worst) was assigned to the participants’ residential locations. We used multivariable regression analyses to examine the association between nSES and the HLI (mean difference with 95% confidence interval, CI) as well as the four individual lifestyle factors (odds ratios (OR) with 95% CI). In sensitivity analyses, nSES was modelled using all seven Social Index categories and as a dichotomy (categories 1–4 vs. 5–7).

Of 204,801 NAKO participants, 31,075 were recruited in Berlin, of those 11,922 with complete accelerometry data were included (mean ± SD age 50.6 ± 12.9 years; 52.8% women). The mean HLI was 8.3 ± 2.0 points. Worsening of nSES by one point was associated with a 0.08-point lower HLI (-0.08 (95%-CI -0.10; -0.06)), with a reduced odds of normal weight (0.95; 0.93–0.97) and being a never-smoker (0.96; 0.94–0.98), while it was neither associated with alcohol consumption (1.01; 0.99–1.04)) nor physical activity (0.99; 0.97–1.02)). Sensitivity analyses suggested that differences were mainly driven by a contrast between categories 1–4 and the more disadvantaged categories 5–7. However, the overall pattern of results did not change.

Our analyses suggest a rather small association between Berlin’s nSES and HLI, and slightly stronger associations with BMI and smoking. Future studies using longitudinal data and more neighbourhood measures are needed to better disentangle contextual influences from residential selection and to inform targeted prevention strategies.

The online version contains supplementary material available at 10.1186/s12889-026-26734-5.

## Full-text entities

- **Diseases:** HLI (MESH:D000067329), nSES (MESH:D013226)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13037057/full.md

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Source: https://tomesphere.com/paper/PMC13037057