# First person – Niranjan Joshi

PMC · DOI: 10.1242/bio.062531 · Biology Open · 2026-03-09

## TL;DR

This paper discusses how aPKC and F-actin dynamics influence Hippo pathway polarity in asymmetrically dividing neuroblasts.

## Contribution

The study reveals new insights into the role of aPKC and F-actin in Hippo pathway polarity during asymmetric neuroblast division.

## Key findings

- aPKC and F-actin dynamics are crucial for Hippo pathway polarity in neuroblasts.
- The findings highlight the importance of these dynamics in asymmetric cell division.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Niranjan Joshi is first author on ‘
aPKC and F-actin dynamics promote Hippo pathway polarity in asymmetrically dividing neuroblasts’, published in BIO. Niranjan conducted the research described in this article while an undergraduate research assistant in Dr Richard Fehon's lab at The University of Chicago, Chicago, IL, USA. He is now a research technician in the lab of Dr Stefano Di Talia at Duke University, Durham, NC, USA, investigating how development emerges from the dynamic features of molecules, cells and tissues.

## Linked entities

- **Genes:** aPKC (atypical protein kinase C) [NCBI Gene 47594]
- **Proteins:** aPKC (atypical protein kinase C), Act5C (Actin 5C)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13035060/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13035060/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC13035060/full.md

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Source: https://tomesphere.com/paper/PMC13035060