# Disseminated Nocardia paucivorans infection in a 64-year-old patient with first manifestation as an ulnocarpal forearm lesion

**Authors:** Peter Mohos, Lukas Mathys, Céline Bratschi, Georg Julian Claas, Philipp Honigmann, Marco Keller

PMC · DOI: 10.1080/23320885.2026.2643076 · Case Reports in Plastic Surgery & Hand Surgery · 2026-03-28

## TL;DR

A 64-year-old cancer patient developed a rare Nocardia infection starting as a forearm lesion and spreading to the lungs and brain.

## Contribution

This case highlights Nocardia paucivorans as a disseminated infection in immunocompromised patients with cancer.

## Key findings

- Nocardia paucivorans was identified in a forearm lesion of an immunocompromised patient.
- PET-CT and MRI showed pulmonary and cerebral involvement of the infection.
- Antimicrobial therapy reduced brain lesions, but the patient died from the underlying cancer.

## Abstract

We report a 64-year-old immunocompromised patient receiving chemotherapy for metastatic colorectal adenocarcinoma who presented with a purulent forearm lesion. Surgical debridement identified Nocardia paucivorans. PET-CT and MRI revealed pulmonary and cerebral involvement. Escalated antimicrobial therapy achieved complete regression of brain lesions; the patient died 11 months later from underlying disease.

## Linked entities

- **Species:** Nocardia paucivorans (taxon 114259)

## Full-text entities

- **Diseases:** colorectal adenocarcinoma (MESH:D003110), Nocardia paucivorans infection (MESH:D009617), brain lesions (MESH:D001927), pulmonary and cerebral involvement (MESH:C566343), forearm lesion (MESH:D005543)
- **Species:** Homo sapiens (human, species) [taxon 9606], Nocardia paucivorans (species) [taxon 114259]

## Full text

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## Figures

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## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC13034707/full.md

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Source: https://tomesphere.com/paper/PMC13034707