# Clinical Presentation, Management, and Outcomes of Access-Related Radial Artery Pseudoaneurysms: A Single-Center, Retrospective Cohort Study

**Authors:** Michael Vlach, Aqsa Choudhry, Rhythm Vasudeva, Mohinder Vindhyal, Prasad Gunasekaran, Gaurav Parmar, Georges Haj, J.D. Serfas, Mark Wiley, Peter Tadros, Eric Hockstad, Anthony Spaedy, Seth Decamp, Kamal Gupta

PMC · DOI: 10.1016/j.jscai.2025.104065 · Journal of the Society for Cardiovascular Angiography & Interventions · 2025-12-09

## TL;DR

This study examines radial artery pseudoaneurysms after medical procedures, finding they often appear days later and are more common in women and those on blood thinners.

## Contribution

The study provides new clinical insights into the presentation, treatment success rates, and risk factors for radial artery pseudoaneurysms.

## Key findings

- Radial artery pseudoaneurysms typically present 13 days after procedures but symptoms begin within a day.
- Mechanical compression succeeds in 47.4% of cases, while surgery is nearly always successful.
- Earlier diagnosis and smaller size predict successful compression outcomes.

## Abstract

Radial artery pseudoaneurysm (RAP) is a rare complication of procedural radial access. There is a paucity of data regarding clinical presentation, characteristics, and management.

We identified patients with RAP by querying our center’s electronic medical records. A manual chart review was performed, and a descriptive analysis was conducted.

We identified 35 patients with RAP (mean age, 68.3 years; 62.9% women). Of these, 71.4 % of pseudoaneurysms were caused by arterial access for coronary procedures. Sixty percent were on anticoagulation. The most common symptoms were swelling (88.6%) and pain (45.7%). The median time from procedure to diagnosis was 13 days (IQR, 1-33.5 days), and the median time from procedure to symptom onset was 1 day (IQR, 0-8.5 days). Initial treatment modality was mechanical compression in 19 patients (54.3%). Of those who underwent compression, the RAP thrombosed in 9 patients (47.4%) and failed in 10 patients (52.6%) who then underwent successful surgical repair. Those with RAP resolution with compression had a shorter time to ultrasound diagnosis (1 vs 6.5 days) and smaller size (1.6 vs 2.4 cm). Surgery was successful in all but 1 patient.

Study findings show that RAPs often present several days after the index procedure, although symptoms occur much earlier. The RAPs occur disproportionately in women and those on anticoagulation. Compression is successful in only half the patients. Earlier presentation and smaller size predict success. Surgery is almost universally successful, and thrombin injection is rarely used. Our results suggest a need for prospective studies to assess strategies for earlier identification of RAP.

## Full-text entities

- **Genes:** F2 (coagulation factor II, thrombin) [NCBI Gene 2147] {aka PT, RPRGL2, THPH1}
- **Diseases:** embolization (MESH:D004617), wound dehiscence (MESH:D013529), congestive heart failure (MESH:D006333), pain (MESH:D010146), hypertension (MESH:D006973), hematoma (MESH:D006406), coronary artery disease (MESH:D003324), swelling (MESH:D004487), hand ischemia (MESH:D007511), Compression (MESH:D009408), RAP (MESH:D017541), radial artery injury (MESH:D020425), PV (MESH:D011087), bleeding (MESH:D006470), peripheral arterial disease (MESH:D058729), radial artery occlusion (MESH:D001157), Radial Aneurysm (MESH:D000783), hyperlipidemia (MESH:D006949), obesity (MESH:D009765)
- **Chemicals:** RAA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC13033806/full.md

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Source: https://tomesphere.com/paper/PMC13033806