# First Report of Intentional Intraplaque Lithotripsy After Aggressive Wire Recanalization in Calcified Atheroma and Dilatation (ARCADIA-SHOCK)

**Authors:** Jeffrey C.Y. Lee, Timothy H.H. Kam, Yasunari Sakamoto, Guangming Tan, Bryan P. Yan

PMC · DOI: 10.1016/j.jscai.2025.104106 · Journal of the Society for Cardiovascular Angiography & Interventions · 2025-12-11

## TL;DR

This paper reports the first successful use of intentional intraplaque lithotripsy to treat calcified arteries in a patient with peripheral arterial disease.

## Contribution

The first reported case of intentional intraplaque lithotripsy as a new technique for treating eccentric calcified atheroma.

## Key findings

- Intraplaque lithotripsy was successfully used to treat heavily calcified superficial femoral arteries.
- The procedure was performed without complications in a claudicant patient.
- This technique may offer a safer alternative to atherectomy for eccentric calcium.

## Abstract

Eccentric calcified plaque remains a challenge in the endovascular treatment of peripheral arterial disease despite technological advancements. The "aggressive wire recanalization in calcified atheroma and dilatation" technique was invented to overcome this by intentional intraplaque wiring followed by atherectomy; however, distal embolization can ensue. Substitution with intravascular lithotripsy may be safer and equally effective. To the best of our knowledge, we performed the first case of intentional intraplaque lithotripsy to successfully treat a claudicant patient with heavily calcified bilateral superficial femoral arteries without complications. This may be considered a new technique variation to treat eccentric calcium.

## Linked entities

- **Diseases:** peripheral arterial disease (MONDO:0005386)

## Full-text entities

- **Diseases:** calcification (MESH:D002114), Calcified (MESH:D018333), SFA stenosis (MESH:D003251), embolization (MESH:D004617), EPD (MESH:D009471), ARCADIA (MESH:D058226), coronary chronic total occlusions (MESH:D054059), SHOCK (MESH:D012769), PAD (MESH:D058729), pseudoaneurysm (MESH:D017541), SFA disease (MESH:D004194), dissection (MESH:D000784), claudicant (MESH:D007383), restenosis (MESH:D023903)
- **Chemicals:** calcium (MESH:D002118), Astato XS 20 (-), luminal (MESH:D010634)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13033801/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC13033801/full.md

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Source: https://tomesphere.com/paper/PMC13033801