BlastoDB: first release of a community-driven multi-omics and epidemiological resource for Blastocystis biology and subtyping

TL;DR

BlastoDB is a new open-access database for studying Blastocystis, integrating various data types to support research and collaboration.

Contribution

BlastoDB introduces a community-driven, multi-omics platform for Blastocystis biology and subtyping.

Findings

BlastoDB offers curated data including genomics, transcriptomics, and epidemiological information.

The platform supports subtype classification and integrative analyses through a structured data model and web interface.

Abstract

BlastoDB (
https://www.blastodb.com/) is developed as an open-access, community-driven resource dedicated to
Blastocystis, one of the most common yet understudied intestinal protists. BlastoDB will offer the scientific community up-to-date, curated information on
Blastocystis by integrating epidemiological data, microbiome profiles, multi-omics datasets (genomics, transcriptomics, proteomics, and metabolomics), reference sequences for subtypes, protocols, microscopy images, and related metadata. In this initial release, we describe the data model, database architecture, curation pipelines, and web interface, which together facilitate subtype classification, comparative and integrative analyses, and cross-study synthesis of epidemiological and experimental data. We outline submission and governance workflows designed to support community contributions, training activities, and sustainable curation under the “
Blastocystis under One Health” COST Action (CA21105). Finally, we highlight planned extensions, including expanded metagenomic and metatranscriptomic content, automated genome quality assessments, metagenome-assembled genomes, and geospatial and analytical dashboards. BlastoDB provides a central, FAIR-aligned hub for
Blastocystis data, images, and protocols, reducing technical barriers and fostering a collaborative ecosystem for studying this globally prevalent protist.

Figures