# Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients: A Systematic Review of Long-Term Outcomes

**Authors:** Karam Khasawneh, Mohamed Alzandani, Ghaeth Khasawneh, John Obeid, Christopher Bobier

PMC · DOI: 10.7759/cureus.104196 · 2026-02-24

## TL;DR

This paper compares long-term outcomes of two heart valve replacement methods in low-risk patients, finding similar survival but differing complication rates.

## Contribution

The study provides a systematic review comparing long-term outcomes of TAVR and SAVR in low-risk patients, highlighting variability in durability and re-intervention rates.

## Key findings

- Randomized studies show similar long-term survival and stroke rates between TAVR and SAVR.
- Observational studies suggest worse late outcomes with TAVR compared to SAVR.
- TAVR is associated with fewer postoperative complications but variable valve durability.

## Abstract

The role of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) continues to expand, yet uncertainty remains regarding the long-term outcomes in low-risk populations compared with surgical aortic valve replacement (SAVR). This systematic review examined long-term mortality, stroke, postoperative complications, and valve durability across randomized and observational studies. Randomized data showed similar long-term survival and stroke rates between TAVR and SAVR, while observational studies suggested worse late outcomes following TAVR. TAVR was consistently associated with fewer postoperative complications, whereas durability and re-intervention findings varied across studies. Overall, these results suggest that while TAVR offers meaningful advantages, treatment decisions should be individualized to balance a patient's comorbidities with long-term procedural outcomes.

## Linked entities

- **Diseases:** aortic stenosis (MONDO:0042981)

## Full-text entities

- **Diseases:** AS (MESH:D001024), stroke (MESH:D020521), postoperative (MESH:D019106)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13032847/full.md

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Source: https://tomesphere.com/paper/PMC13032847