# Geometrical analysis of the BeFlared bridging stent-graft in fenestrated endovascular aneurysm repair

**Authors:** Natasha Hasemaki, Zicheng Wan, Jan Stana, Alexia-Vasiliki Amvrazi, Baban Assaf, David Khangholi, Nikolaos Konstantinou, Nikolaos Tsilimparis

PMC · DOI: 10.1186/s42155-026-00670-2 · 2026-03-28

## TL;DR

This study evaluates the BeFlared stent-graft in complex aortic aneurysm repairs, showing high technical success and favorable early outcomes.

## Contribution

The study introduces a geometrical analysis of the BeFlared stent-graft in fenestrated endovascular aneurysm repair.

## Key findings

- 100% technical success rate with no endoleaks or reinterventions at 30-day follow-up.
- Geometric parameters like protrusion length and flare ratio were within optimal ranges for both renal and visceral stent-grafts.

## Abstract

To evaluate the geometrical configuration of the BeFlared bridging stent-graft and the early clinical outcomes in fenestrated endovascular aneurysm repair (FEVAR) for complex abdominal and thoracoabdominal aortic aneurysms.

This retrospective single-center study included 23 consecutive patients who underwent FEVAR using at least one BeFlared stent-graft between December 2024 and June 2025. Technical and clinical data were collected prospectively. Geometrical analysis of the stent-graft configuration was performed using postoperative computed tomography angiography (CTA) at 1 month.

A total of 70 target vessels (TVs) were treated with BeFlared stent-grafts, achieving a 100% technical success rate. No TV-related endoleaks, instability, or reinterventions were observed at 30-day follow-up. Geometric analysis demonstrated a mean protrusion length of 5.27 ± 0.87 mm and a flare ratio of 0.96 ± .03. The mean protrusion length was 5.4 ± .12 mm for renal stent-grafts and 5.1 ± .18 mm for visceral stent-grafts (p = .155). The mean flare ratio was higher in renal stent-grafts (0.97 ± .03) compared to visceral stent-grafts (0.95 ± .03), (p = .045), though both were within optimal ranges. The mean opening flaring angle was 42.3° ± 19.1 for renal stent-grafts and 41.2° ± 19.4 for visceral stent-grafts (p = .809).

Early clinical and technical outcomes of the BeFlared stent-graft in FEVAR are promising, with satisfactory procedural performance and favorable geometric configuration. Larger, multicenter studies with longer follow-up are essential to confirm long-term durability and clinical benefit.

## Full-text entities

- **Diseases:** Ic, Type IIIb or Type IIIc (MESH:D009084), FEVAR (MESH:D000783), abdominal aortic aneurysms (MESH:D017544), ruptured aneurysm (MESH:D017542), aortogastric fistula (MESH:D005402), stenosis (MESH:D003251), renal stenosis (MESH:D012078), AAAs (MESH:C536008), TVI (MESH:C536223), occlusion (MESH:D001157), endoleak (MESH:D057867), fracture (MESH:D050723), TAAAs (MESH:D000094624), multiorgan failure (MESH:D051437), CMD (MESH:D009471)
- **Chemicals:** Advanta (-), chromium (MESH:D002857), cobalt (MESH:D003035), aspirin (MESH:D001241), clopidogrel (MESH:D000077144)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13031677/full.md

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Source: https://tomesphere.com/paper/PMC13031677