# Impact of the COVID-19 Pandemic on Routine Childhood Vaccination in Oklahoma

**Authors:** Jessica Beetch, Laura A. Beebe, Amanda Janitz, Chao Xu, Mary Gowin, Katrin Gaardbo Kuhn

PMC · DOI: 10.3390/vaccines14030271 · Vaccines · 2026-03-19

## TL;DR

The study found that routine childhood vaccinations in Oklahoma dropped during the COVID-19 pandemic, especially for DTaP and MMR vaccines.

## Contribution

This study provides state-specific evidence of pandemic-related disruptions to childhood vaccination in Oklahoma, highlighting the need for targeted strategies.

## Key findings

- DTaP and MMR vaccine doses administered declined during all pandemic phases in Oklahoma.
- Infants were less likely to complete DTaP dosing during the pandemic compared to pre-pandemic periods.

## Abstract

Background/Objectives: The COVID-19 pandemic substantially disrupted routine childhood vaccination practices across the United States. Oklahoma, a state characterized by lower socioeconomic indicators and higher levels of vaccine hesitancy, may have been particularly vulnerable to these disruptions. This study aimed to assess the impact of the COVID-19 pandemic on routine childhood vaccination in Oklahoma. Methods: Data were obtained from the Oklahoma State Immunization Information System to examine changes in the administration of DTaP and MMR vaccines before and during the COVID-19 pandemic, stratified by pandemic phase. Percentage changes in vaccine doses administered were calculated across time periods. Log-binomial regression models were used to evaluate the association between pandemic timing and receipt of subsequent DTaP doses among children under one year of age. Results: Administration of both DTaP and MMR vaccines declined during the COVID-19 pandemic across all pandemic phases examined. Compared with the pre-pandemic period, fewer children returned for subsequent DTaP doses during the pandemic. Regression analyses indicated a reduced likelihood of completing age-appropriate DTaP dosing among infants during the pandemic. Conclusions: Routine childhood vaccination in Oklahoma declined during the COVID-19 pandemic, with persistent reductions observed across pandemic phases. These findings highlight vulnerabilities in vaccination delivery during public health emergencies and underscore the need for targeted state-level strategies to sustain routine immunization services during future crises.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** pertussis (MESH:D014917), even death (MESH:D003643), injury to (MESH:D014947), DTaP (MESH:D013746), diphtheria (MESH:D004165), infection (MESH:D007239), hearing loss (MESH:D034381), COVID-19 (MESH:D000086382), paralysis (MESH:D010243), MMR (MESH:D009107)
- **Chemicals:** DTaP (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13030722/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC13030722/full.md

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Source: https://tomesphere.com/paper/PMC13030722