# Pathogenicity, Resistance Genes and Integrated Management Strategies of Potato Virus Y in Potato

## TL;DR

This paper explores how Potato Virus Y infects potato plants and discusses new resistance genes and strategies to manage the virus.

## Contribution

The paper highlights recent advances in PVY resistance genes and proposes multi-pronged management strategies.

## Key findings

- PVY uses proteins to interact with host factors for replication and infection.
- Potato plants detect PVY effectors through immune receptors and activate defenses.
- New resistance genes like Rysto and Rychc offer potential for managing PVY.

## Abstract

Potato virus Y (PVY), widely regarded as one of the world’s most important plant viruses, seriously threatens global potato production and food security. PVY deploys its proteins to interact with key host factors, thereby enabling viral replication, accumulation, and systemic infection. PVY also exhibits high genetic diversity and frequent recombination, which promote host adaptation and immune evasion. In response, potato plants perceive viral effectors through intracellular immune receptors and activate antiviral defenses. Over the past decade, significant progress has been made in elucidating PVY–host defense and counter-defense mechanisms. Here, we summarize the molecular basis of PVY pathogenicity and highlight recent advances in PVY resistance genes (e.g., Rysto and Rychc). Finally, we integrate emerging insights from plant virology and nucleotide-binding leucine-rich repeat (NLR) biology to discuss prospective, multi-pronged strategies for PVY management.