# PM2.5 and Asthma Disparity in Relation to Social Vulnerability Index: A Case Study from Durham, North Carolina

**Authors:** Macie D. Bethea, Sterling Brown, Sara Harrison, John Bang, James Harrington, Vijay Sivaraman

PMC · DOI: 10.3390/toxics14030221 · Toxics · 2026-03-04

## TL;DR

This study shows that higher PM2.5 levels in South Durham correlate with higher asthma rates and social vulnerability compared to North Durham.

## Contribution

The study links PM2.5 elemental composition differences to asthma disparities and social vulnerability in Durham.

## Key findings

- South Durham has higher PM2.5 levels (78.49 µg/m3) compared to North Durham (26.3 µg/m3).
- PM2.5 in South Durham contains higher levels of elements like Na, S, Ca, Mg, Fe, and Ti.
- Higher pollution in South Durham correlates with increased asthma hospitalizations and social vulnerability.

## Abstract

Increased air pollution and associated disease prognosis are a serious concern in communities across the socioeconomic spectrum. Past studies have shown that a major component of air pollution, fine particulate matter (PM2.5), is elevated in majority-Black communities in the US to greater levels than those in majority-White communities, which can potentially contribute to higher rates of respiratory health issues. In this study, we address whether PM2.5 correlates with increased asthma rates in Durham, North Carolina. We selected monitoring sites in different census tracts within the same zip code with disparate levels of asthma to quantify and characterize PM2.5 levels. We found that South Durham, which has higher asthma hospitalization rates, has higher average PM2.5 levels (78.49 µg/m3) than North Durham (26.3 µg/m3). We measured the elemental composition of PM samples using transmission electron microscopy–energy dispersive X-ray spectroscopy (TEM-EDX) and found significant differences in the levels of Na, S, Ca, Mg, Fe, and Ti. Our data suggests that these differences in ambient PM2.5 could contribute to differences in health outcomes in the two areas. We also discuss these differences in the context of social vulnerability within the two study sites and show that the more vulnerable site (South Durham) experiences higher pollution rates.

## Linked entities

- **Chemicals:** Na (PubChem CID 923), S (PubChem CID 3015009), Ca (PubChem CID 271), Mg (PubChem CID 888), Fe (PubChem CID 23925), Ti (PubChem CID 23963)
- **Diseases:** asthma (MONDO:0004979)

## Full-text entities

- **Diseases:** cancer (MESH:D009369), NC (OMIM:617025), Pulmonary illness (MESH:D012140), Asthma (MESH:D001249), complications (MESH:D008107), inflammation (MESH:D007249), respiratory health (MESH:D012131), injury to (MESH:D014947), death (MESH:D003643), pulmonary inflammation (MESH:D011014), toxicity (MESH:D064420), COPD (MESH:D029424)
- **Chemicals:** Na (MESH:D012964), Mg (MESH:D008274), silicon (MESH:D012825), lead (MESH:D007854), Ti (MESH:D014025), S (MESH:D013455), Copper (MESH:D003300), nitrogen (MESH:D009584), sulfate (MESH:D013431), cadmium (MESH:D002104), nitrate (MESH:D009566), TEFLON (MESH:D011138), Ni (MESH:D009532), EC (-), chromium (MESH:D002857), manganese (MESH:D008345), Ca (MESH:D002118), ethanol (MESH:D000431), ozone (MESH:D010126), carbon (MESH:D002244), arsenic (MESH:D001151), ammonium (MESH:D064751), Fe (MESH:D007501), potassium (MESH:D011188)
- **Species:** Nicotiana tabacum (American tobacco, species) [taxon 4097], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13029908/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC13029908/full.md

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Source: https://tomesphere.com/paper/PMC13029908