# Evaluation of Pediatric Patients Diagnosed with Cutaneous Leishmaniasis: A Single-Center Experience

**Authors:** Melis Deniz, İsa An, Kerim Parlak, Hasan Tezer

PMC · DOI: 10.3390/tropicalmed11030071 · Tropical Medicine and Infectious Disease · 2026-03-05

## TL;DR

This study examines skin lesions in children with leishmaniasis, highlighting the importance of early diagnosis and treatment to avoid long-term issues.

## Contribution

The study provides insights into clinical features and treatment outcomes specific to pediatric cutaneous leishmaniasis patients.

## Key findings

- Plaques and ulcerative lesions were the most common lesion types in pediatric patients.
- Multiple-lesion patients had a statistically significant higher use of prior antibiotics.
- Facial and neck regions were most frequently affected in pediatric cases.

## Abstract

Objective: We aimed to describe the clinical features and treatment outcomes of pediatric patients with leishmaniasis. Methods: This retrospective study included pediatric patients (>1 month–18 years) diagnosed with leishmaniasis at Şanlıurfa Training and Research Hospital between January 2022 and January 2024, identified from electronic medical records. Results: Among patients with cutaneous leishmaniasis, fifty pediatric patients were evaluated. Plaques (n = 34, 68%) and ulcerative lesions (n = 8, 16%) were the most common lesion types, with the face and neck being the most frequently affected sites (n = 34, 68%). The number of previously used antibiotics was statistically significantly higher in the multiple-lesion group compared to the single-lesion group (p = 0.022). Conclusions: Clinicians should consider cutaneous leishmaniasis in children with plaque or ulcerative skin lesions and a history of travel to an endemic area. Early detection and timely treatment can prevent long-term damage and cosmetic issues, leading to improved patient outcomes.

## Linked entities

- **Diseases:** leishmaniasis (MONDO:0011989), cutaneous leishmaniasis (MONDO:0005446)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** cutaneous lesion (MESH:D009059), pruritus (MESH:D011537), Infection with (MESH:D007239), ulcerative lesions (MESH:D014456), injury to (MESH:D014947), Adenopathy (MESH:D000072281), MCL (MESH:D007897), mucocutaneous disease (MESH:D004194), depression (MESH:D003866), malnutrition (MESH:D044342), bacterial infections (MESH:D001424), tropical disease (MESH:D015493), CL (MESH:D016773), pain (MESH:D010146), toxicity (MESH:D064420), parasitic disease (MESH:D010272), VL (MESH:D007898), Lymphangitis (MESH:D008205), facial lesions (MESH:D005155), erythema (MESH:D004890), Leishmania infection (MESH:D007896), skin ulcers (MESH:D012883), weight loss (MESH:D015431), Infectious Diseases (MESH:D003141), fever (MESH:D005334), bacterial co-infection (MESH:D060085), inflammatory (MESH:D007249), Skin lesions (MESH:D012871)
- **Chemicals:** antimony (MESH:D000965), Antimonials (-), amphotericin B deoxycholate (MESH:C059765), amphotericin B (MESH:D000666), sodium stibogluconate (MESH:D000967), meglumine antimoniate (MESH:D000077485), pentamidine (MESH:D010419)
- **Species:** Meleagris gallopavo (common turkey, species) [taxon 9103], Staphylococcus aureus (species) [taxon 1280], Leishmania infantum (species) [taxon 5671], Homo sapiens (human, species) [taxon 9606], Leishmania braziliensis (species) [taxon 5660]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13029831/full.md

## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC13029831/full.md

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Source: https://tomesphere.com/paper/PMC13029831