# Anti-Obesogenic Effects of Culinary Herbs Through Modulation of Inflammation and Metabolic Pathways

**Authors:** Anna Winiarska, Agnieszka Tomczyk-Warunek, Karolina Jachimowicz-Rogowska, Małgorzata Kwiecień, Tomasz Czernecki, Magdalena Lis, Waldemar Kazimierczak

PMC · DOI: 10.3390/nu18060993 · Nutrients · 2026-03-20

## TL;DR

This paper reviews how culinary herbs may help prevent obesity by reducing inflammation and improving metabolic health through their bioactive compounds.

## Contribution

The paper systematically reviews the anti-obesogenic potential of culinary herbs via modulation of inflammation and gut microbiota-related metabolic pathways.

## Key findings

- Bioactive compounds in herbs like polyphenols and flavonoids show anti-inflammatory and antioxidant effects.
- Herbs may help reduce obesity risk by improving gut microbiota and metabolic health.
- Using herbs in daily meals could support healthy lifestyle choices and lower cardiovascular disease risk.

## Abstract

Obesity is considered a chronic disease that co-occurs with other disorders, including type 2 diabetes; therefore, the prevention and treatment of obesity are of utmost importance. The present review analysed the effects of bioactive compounds found in culinary herbs on the regulation of inflammatory processes through the modulation of inflammation and microbiota-dependent metabolic pathways. A total of 137 publications from 2010 to 2025 were reviewed. Few studies address the impact of culinary herbs on the gut microbiota in relation to obesity; however, analysing data on the effects of active compounds present in various herbs allows an assessment of their potential role in obesity prevention. This is a significant issue, as obesity is widespread, and the introduction of readily usable everyday food products may represent an important element of preventive strategies. Plant secondary metabolites, such as polyphenols, saponins, alkaloids, and flavonoids, exert strong antioxidant and anti-inflammatory activity, thus contributing to their beneficial effects on human health. Effective weight loss depends on the consistent maintenance of a healthy lifestyle, a requirement that can often be highly challenging. The daily use of herbs in meal preparation may reduce the risk of developing obesity or mitigate its severity. Herbs enhance the flavour of dishes and, additionally, help to reduce salt intake, thereby lowering the risk of cardiovascular disease, which is also an integral component of a healthy lifestyle.

## Linked entities

- **Chemicals:** saponins (PubChem CID 6540709)
- **Diseases:** obesity (MONDO:0011122), type 2 diabetes (MONDO:0005148), cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** type 2 diabetes (MESH:D003924), Obesity (MESH:D009765), weight loss (MESH:D015431), cardiovascular disease (MESH:D002318), Inflammation (MESH:D007249)
- **Chemicals:** saponins (MESH:D012503), salt (MESH:D012492), polyphenols (MESH:D059808), alkaloids (MESH:D000470), flavonoids (MESH:D005419)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

137 references — full list in the complete paper: https://tomesphere.com/paper/PMC13029770/full.md

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Source: https://tomesphere.com/paper/PMC13029770