# The Efficacy of Plant Extracts Against Key Food-Borne Pathogens: A Mechanistic, Applications, and Advances

**Authors:** Seham M. Al Raish

PMC · DOI: 10.3390/microorganisms14030621 · Microorganisms · 2026-03-10

## TL;DR

This paper reviews how plant extracts can fight food-borne pathogens and improve food safety with natural, sustainable methods.

## Contribution

The paper provides a comprehensive review of the antimicrobial potential and mechanisms of plant-derived polyphenolic extracts.

## Key findings

- Plant polyphenolic extracts show strong activity against food-borne pathogens.
- These extracts can help combat antimicrobial resistance and meet consumer demand for natural preservatives.
- They offer potential for use in advanced food preservation systems.

## Abstract

The dual challenge of rising antimicrobial resistance and consumer demand for natural preservatives threatens global food safety. In this context, plant-derived polyphenolic extracts offer a potent and sustainable solution. These compounds exhibit potent activity against key food-borne pathogens responsible for diseases ranging from diarrhea to gastrointestinal ulcers, as well as pathogen-associated inflammatory conditions linked to long-term gastrointestinal complications. This review synthesizes current research on the efficacy of polyphenolic extracts as antimicrobial agents. I detail their diverse mechanisms of action, evaluate their potential for medical applications, and discuss their integration into advanced food preservation systems to meet modern safety and sustainability standards. Collectively, these insights highlight the potential of plant-derived polyphenolic extracts as sustainable tools for improving food safety in modern food systems.

## Linked entities

- **Diseases:** diarrhea (MONDO:0001673)

## Full-text entities

- **Diseases:** diarrhea (MESH:D003967), inflammatory (MESH:D007249), gastrointestinal ulcers (MESH:D014456), gastrointestinal complications (MESH:D005767)
- **Chemicals:** polyphenolic extracts (-)

## Full text

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## Figures

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## References

92 references — full list in the complete paper: https://tomesphere.com/paper/PMC13029504/full.md

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Source: https://tomesphere.com/paper/PMC13029504