# An Exploratory Prospective Intervention Study on Dietary Content and HbA1c in Experiential Nutrition Guidance for Patients with Type 2 Diabetes

**Authors:** Katsumi Iizuka, Akemi Ito, Chihiro Ushiroda, Konomi Hirano, Kanako Deguchi, Izumi Hiratsuka, Megumi Shibata, Takeshi Takayanagi, Yusuke Seino, Kokoro Sano, Atsushi Suzuki

PMC · DOI: 10.3390/nu18060956 · Nutrients · 2026-03-18

## TL;DR

A hands-on nutrition education program improved blood sugar control in type 2 diabetes patients but led to worse body composition.

## Contribution

This study shows that experiential nutrition guidance can lower HbA1c but may increase body fat in elderly diabetes patients.

## Key findings

- HbA1c levels significantly improved after the intervention.
- Carbohydrate intake decreased significantly in female participants.
- Body fat increased significantly while skeletal muscle index decreased in females.

## Abstract

Background: Medical nutrition therapy (MNT) is crucial for diabetes management. This study evaluated a hands-on nutrition education program that incorporated cooking demonstrations for glycemic control, anthropometrics, and dietary behavior over a 2-month period. Methods: Nineteen type 2 diabetes patients (four males and 15 females; 79% female) participated. The median [IQR] age was 70.0 [65.5–73.0] years; the duration of diabetes was 12.0 [8.5–14.0] years; the body mass index (BMI) was 24.3 [21.05–27.90] kg/m2, and the baseline HbA1c level was 6.90 [6.55–7.50%]. Approximately 20–25% of patients used injectable therapies. Pre- and post-treatment comparisons were performed via Wilcoxon signed-rank tests, while effect sizes were quantified via rank–biserial correlation (RBC). Results: In females (n = 15), carbohydrate intake decreased significantly (RBC = −0.583; p = 0.050). The protein levels per 1000 kcal exhibited a strong positive effect (RBC = 0.550; p = 0.065). HbA1c levels improved significantly (overall: RBC = −0.689 and p = 0.009; females: RBC = −0.725 and p = 0.014), and while body fat increased significantly (overall: RBC = 0.979 and p < 0.001; females: RBC = 0.983 and p < 0.001), the skeletal muscle index tended to decrease in females (RBC = −0.333; p = 0.268). Conclusions: Short-term hands-on nutrition education resulted in significant HbA1c improvement and dietary behavior changes but was accompanied by body composition deterioration. The findings of this study clarify the potential risks of nutritional interventions in elderly diabetic patients and provide important insights for improving future programs.

## Linked entities

- **Diseases:** Type 2 Diabetes (MONDO:0005148)

## Full-text entities

- **Diseases:** Type 2 Diabetes (MESH:D003924), diabetes (MESH:D003920)
- **Chemicals:** carbohydrate (MESH:D002241)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

49 references — full list in the complete paper: https://tomesphere.com/paper/PMC13029258/full.md

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Source: https://tomesphere.com/paper/PMC13029258