# Review of Infections in Immunocompromised Travellers: Epidemiology, Infection Prevention and Management

**Authors:** Anca-Elena Duduveche, Andreea-Lacramioara Mohorea-Neata, Sorina-Nicoleta Badelita

PMC · DOI: 10.3390/microorganisms14030721 · Microorganisms · 2026-03-23

## TL;DR

This paper reviews how immunocompromised travelers are at higher risk for infections and outlines strategies for prevention and management.

## Contribution

The paper emphasizes personalized risk assessment and multidisciplinary care for managing infections in immunocompromised travelers.

## Key findings

- Immunocompromised travelers face increased infection risks due to weakened immune systems.
- Pre-travel consultations and destination-specific risk assessments are crucial for prevention.
- Multidisciplinary care involving specialists is essential for effective management.

## Abstract

International travel has increased significantly in recent years. Many travellers are immunocompromised, making them more susceptible to infectious diseases due to their weakened immune systems. This narrative review provides an overview of infection epidemiology, prevention strategies, and clinical management for immunocompromised travellers. We demonstrate the role of pre-travel consultation, emphasizing individualized risk assessment informed by destination-specific epidemiology, immune status, and underlying conditions. Key preventive interventions, including vaccination strategies, antimicrobial prophylaxis, and detailed health counseling, in addition to practical measures that can be taken to minimize infection risk during travel, are addressed. Post-travel surveillance and early recognition of travel-related infections are analyzed, highlighting the importance of prompt symptom evaluation. Effective care for immunocompromised travellers requires a multidisciplinary framework that integrates patients, primary care physicians, infectious disease specialists, and travel medicine experts.

## Full-text entities

- **Diseases:** Infection (MESH:D007239), infectious disease (MESH:D003141)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC13028676/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13028676/full.md

## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC13028676/full.md

---
Source: https://tomesphere.com/paper/PMC13028676