# Constraint-Induced Movement Therapy in the Rehabilitation of Adults After Stroke: An Umbrella Review

**Authors:** José Conchillo-Liria, Iván Cavero-Redondo, Alicia Saz-Lara, Nerea Moreno-Herraiz, Candela Calvo-Utrilla, Ana González-Collado, Iris Otero-Luis

PMC · DOI: 10.3390/jcm15062451 · Journal of Clinical Medicine · 2026-03-23

## TL;DR

Constraint-induced movement therapy helps stroke patients recover upper limb function and improve daily living activities, especially in later recovery stages.

## Contribution

This umbrella review systematically evaluates CIMT's effectiveness across multiple outcomes and stages of stroke recovery.

## Key findings

- CIMT significantly improves upper limb motor function in stroke patients.
- Intensive CIMT interventions strongly enhance independence in daily living activities.
- CIMT contributes to improved quality of life in post-stroke rehabilitation.

## Abstract

Background/Objectives: Stroke is among the leading causes of disability in adults, as hemiparesis affects motor function and daily activities. Constraint-induced movement therapy (CIMT) has proven effective in functional recovery through intensive use of the affected limb. This study aimed to assess the impact of CIMT on upper limb (UL) rehabilitation in stroke patients, with a focus on motor recovery, integration into activities of daily living (ADLs), and overcoming clinical implementation barriers. Methods: A systematic review was conducted by searching PubMed, Scopus, and Web of Science from their inception to March 2026. Systematic reviews and meta-analyses evaluating the effectiveness of CIMT in adult patients after stroke were included. The outcome variables included motor function, movement quality, independence in ADLs, and quality of life (QoL). Results: Twenty-five systematic reviews and sixteen meta-analyses were included. The participants were adults who had suffered a stroke at acute, subacute, or chronic stages and were aged between 18 and 95 years. With respect to upper limb motor function, ten studies reported statistically significant results in favor of CIMT. With respect to ADLs, four studies reported significant differences in favor of CIMT, with strong effects in intensive interventions. With respect to QoL, three studies reported significant improvements after the intervention. Conclusions: The results of this umbrella review support the effectiveness of CIMT in UL rehabilitation after stroke, especially in the subacute and chronic phases. CIMT, alone or in combination with adjuvant therapies, contributes to improving motor function, independence in ADLs, and QoL in patients.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** disability (MESH:D009069), Stroke (MESH:D020521), hemiparesis (MESH:D010291)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC13028200/full.md

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Source: https://tomesphere.com/paper/PMC13028200