# Ocular Color Doppler Ultrasound (OCDUS) in Diagnosis and Monitoring of Ophthalmological, Cerebrovascular and Systemic Diseases: A Narrative Review

**Authors:** Massimo Venturini, Silvia Malnati, Noemi Teresa Catania, Andrea Coppola, Chiara Recaldini, Aroa Gnesutta, Marianna Ciani, Silvia Tamietti, Emilio Simonini, Alberta Cappelli, Simone Donati, Filippo Piacentino, Federico Fontana

PMC · DOI: 10.3390/jcm15062458 · Journal of Clinical Medicine · 2026-03-23

## TL;DR

This review explores how ocular color Doppler ultrasound can help diagnose and monitor various eye, brain, and systemic diseases.

## Contribution

The paper highlights the underutilized potential of OCDUS in diagnosing and monitoring multiple disease categories.

## Key findings

- OCDUS provides quantitative and reproducible measurements of orbital blood flow.
- The technique has been used in studies for ophthalmological, cerebrovascular, and systemic disease monitoring.
- Current literature supports OCDUS as a relevant imaging modality for these conditions.

## Abstract

Ocular Color Doppler ultrasound (OCDUS) has been underutilized in the past as a diagnostic technique, although several OCDUS-based studies were performed in the last 30 years for diagnosis or monitoring of some ophthalmological, cerebrovascular or systemic diseases. OCDUS can provide quantitative and reproducible measurements of the blood flow of the main orbital vessels at the retrobulbar level. In this narrative review we aimed to investigate the relevance of OCDUS as an imaging modality in several ophthalmological, cerebrovascular and systemic diseases based on the current literature.

## Full-text entities

- **Diseases:** Ophthalmological, Cerebrovascular and Systemic Diseases (MESH:D002561)

## Full text

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## Figures

16 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13028183/full.md

## References

199 references — full list in the complete paper: https://tomesphere.com/paper/PMC13028183/full.md

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Source: https://tomesphere.com/paper/PMC13028183