# The Use of Topical Lidocaine Versus Lidocaine Injection for Myringotomy and Ventilation Tube Insertion

**Authors:** Filip Bacan, Emili Dragaš, Mirta Peček, Iva Kelava, Andro Košec, Mihael Ries, Jakov Ajduk

PMC · DOI: 10.3390/medicina62030595 · Medicina · 2026-03-21

## TL;DR

This study compares pain levels from lidocaine spray versus injections during ear procedures, finding that spray causes less pain.

## Contribution

The study demonstrates that topical lidocaine is a less painful alternative to injections for ear surgeries.

## Key findings

- Topical lidocaine resulted in significantly lower pain scores compared to injections on VAS and NRS.
- Patients reported consistently lower pain levels with lidocaine spray during myringotomy and tube insertion.
- Logistic regression showed a trend toward lower pain with spray, though not statistically significant for VRS.

## Abstract

Background and Objectives: Minor otologic procedures in adults are often performed under local anesthesia, either via injection or topical application, thereby avoiding general anesthesia-associated risks. This study aims to compare pain levels with the use of a lidocaine spray versus lidocaine injections. Materials and Methods: Fifty adult patients underwent local anesthetic myringotomy and ventilation tube placement, 30 unilaterally, and 20 bilaterally. Lidocaine injections were administered to 29 patients, and 21 received a lidocaine spray. Postoperatively, they were asked to mark their perceived pain level on a visual analogue scale (VAS, 0–100 mm), verbal rating scale (VRS, 0–3), and numeric rating scale (NRS, 0–10). Data normality was assessed using the Shapiro–Wilk test, continuous variables were analyzed using analysis of variance (ANOVA), and VRS outcomes were analyzed using binary logistic regression. A p-value ≤ 0.05 indicated statistical significance. Results: Pain levels were low in both groups, although consistently lower in the topical lidocaine group. The average VAS score was 23.14 mm (±14.69) for injection versus 9.76 mm (±11.41) for topical anesthesia (ANOVA, p = 0.002), while NRS scores averaged at 2.41 (±1.57) and 1.19 (±1.17), respectively (ANOVA, p = 0.009), indicating significantly lower pain with topical lidocaine. Logistic regression of the VRS indicated the same trend, although it did not reach statistical significance (OR = 0.153, 95% CI:0.017–1.389, p = 0.095). Conclusions: Lidocaine spray was associated with lower pain levels compared to lidocaine injections in patients undergoing myringotomy and ventilation tube placement. Our findings suggest that topical anesthesia may represent an effective alternative, offering a less invasive approach and reducing the needle-related psychological distress of patients.

## Linked entities

- **Chemicals:** lidocaine (PubChem CID 3676)

## Full-text entities

- **Diseases:** Pain (MESH:D010146)
- **Chemicals:** Lidocaine (MESH:D008012)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC13028150/full.md

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Source: https://tomesphere.com/paper/PMC13028150