Stimuli-Responsive Nanomaterial-Based Biosensor Structures for Wound Care: pH, ROS, and Temperature Sensing Strategies
Anita Ioana Visan, Adrian Birnaz, Irina Negut
TL;DR
This paper reviews smart wound-care systems using nanomaterial-based biosensors to monitor pH, ROS, and temperature for better wound healing and infection detection.
Contribution
The paper provides a systematic review of stimuli-responsive nanomaterial-based biosensors for wound care, emphasizing multimodal and theranostic platforms.
Findings
Nanomaterial-based biosensors can continuously monitor wound pH, ROS, and temperature.
Multimodal platforms integrate sensing with drug release and therapy for adaptive wound management.
Future wound care could combine nanomaterials, self-powered electronics, and data processing for personalization.
Abstract
Chronic and infected wounds remain a major clinical challenge due to their dynamic microenvironments and the lack of real-time diagnostic feedback in conventional dressings. Recent advances in stimuli-responsive nanomaterial-based biosensors have enabled the development of smart wound-care systems capable of continuous monitoring and on-demand therapeutic intervention. This review systematically summarizes progress in nanomaterial-enabled wound biosensing strategies, with a focus on pH, reactive oxygen species, and temperature nanosensors, which serve as key indicators of infection, inflammation, and healing status. We discuss the sensing mechanisms and functional roles of diverse nanomaterials. A particular focus is placed on emerging multimodal and theranostic platforms which integrate biochemical and physical sensing with controlled drug release, photothermal or photodynamic therapy,…
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Taxonomy
TopicsWound Healing and Treatments · Nanoplatforms for cancer theranostics · Carbon and Quantum Dots Applications