The Role of Transcranial Magnetic Stimulation for the Treatment of Alzheimer’s Disease: A Narrative Review

TL;DR

This review explores how transcranial magnetic stimulation might help treat Alzheimer's disease, a common form of dementia with limited treatment options.

Contribution

The paper provides a narrative review of TMS as a novel non-invasive treatment approach for Alzheimer's disease.

Findings

TMS is a promising non-invasive neuromodulation technique for Alzheimer's disease.

Current drug therapies for AD offer only limited symptomatic relief, highlighting the need for new approaches.

TMS's clinical efficacy, safety, and underlying mechanisms in AD are reviewed and evaluated.

Abstract

Alzheimer’s disease (AD) is the most common neurodegenerative disease that accounts for 60–80% of all dementia cases and affects millions of people worldwide. At present, standard drug therapies provide only limited symptomatic relief. Therefore, the exploration of novel therapeutic approaches is crucial for improving patient outcomes. Transcranial magnetic stimulation (TMS) has emerged as a promising non-invasive neuromodulation technique that may provide benefit in AD management. This review discusses the pathophysiological mechanisms by which TMS operates, evaluates its clinical efficacy in AD patients, assesses its safety profile, and suggests future directions for research.

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