# Sexual Functioning of Patients with Inflammatory Bowel Disease

**Authors:** Marta Kotkowicz-Szczur, Lidia Kisielewska, Rafal Kisielewski, Maciej Kierzkiewicz, Jaroslaw Kierkus, Edyta Szymanska

PMC · DOI: 10.3390/jcm15062379 · 2026-03-20

## TL;DR

This study shows that inflammatory bowel disease negatively affects patients' sexual functioning, especially during disease flare-ups.

## Contribution

The study provides empirical evidence of the specific sexual impacts of IBD clinical activity.

## Key findings

- IBD diagnosis significantly decreases sexual satisfaction in 34% of patients.
- Active IBD correlates with reduced sexual desire, frequency, and duration of intercourse.
- More aggressive disease courses lead to greater negative impacts on sexual functioning and body image.

## Abstract

Background/Objectives: Chronic diseases, such as inflammatory bowel disease (IBD), influence patients’ sexuality. Therefore, the aim of this study was to analyze the sexual functioning (SF) of patients with IBD. Methods: We perform a prospective survey study on male and female individuals with IBD using an anonymous questionnaire including 60 inquiries concerning patients’ intimate relationships and SF. The following statistical tests were used: chi-square test of independence, Spearman’s rank correlation coefficient, and Wilcoxon and Mann–Whitney U tests. A significance level of p = 0.05 was assumed as statistically significant. Results: There were 110 respondents with IBD (41% with Crohn’s disease and 57% with ulcerative colitis): 52 women (47%) and 58 men (53%), with a mean age of between 31 and 40 (45%). In 34% of respondents, the assessment of satisfaction with sex after diagnosis decreased, and the difference was statistically significant (p = 0.007). Statistically significant correlations were found between IBD clinical activity and the impact of the disease on sexual desire (p < 0.001), the need for sex after diagnosis (p < 0.001), satisfaction with sex after diagnosis (p = 0.003), the average frequency of intercourse (p = 0.004), the average duration of intercourse after diagnosis (p = 0.001), feeling guilty in the sexual sphere due to the disease (p = 0.006), assessment of one’s attractiveness since diagnosis (p = 0.032), and change in the partner’s erotic perception after diagnosis (p < 0.001). The more aggressive the course of the disease, the more negative the impact on patients’ sexuality. Conclusions: The diagnosis of IBD has a negative impact on patients’ SF—disease flare leads to a decrease in sexual needs, worse experiences and negative body image.

## Linked entities

- **Diseases:** inflammatory bowel disease (MONDO:0005265), Crohn's disease (MONDO:0005011), ulcerative colitis (MONDO:0005101)

## Full-text entities

- **Diseases:** Chronic diseases (MESH:D002908), ulcerative colitis (MESH:D003093), Crohn's disease (MESH:D003424), IBD (MESH:D015212)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13027302/full.md

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Source: https://tomesphere.com/paper/PMC13027302