# Mechanical Complications After Acute Myocardial Infarction: A Shock-Stage and Timing-Based Management Framework

**Authors:** Caius Glad Streian, Ramona Cristina Novaconi, Iulia Raluca Munteanu, Andrei Raul Manzur, Adrian Grigore Merce, Marciana Ionela Boca, Lucian Silviu Falnita, Ciprian Nicusor Dima, Adrian Petru Merce, Silvius Alexandru Pescariu, Dan Iliescu, Dragos Cozma, Horea Bogdan Feier

PMC · DOI: 10.3390/jcm15062399 · Journal of Clinical Medicine · 2026-03-21

## TL;DR

This paper reviews how to manage rare but deadly heart complications after heart attacks, focusing on timing and treatment decisions based on shock severity.

## Contribution

The paper introduces a unified framework and a structured checklist (STABLE) for managing mechanical complications after heart attacks.

## Key findings

- Mechanical complications like ventricular septal rupture remain deadly despite advances in treatment.
- A new framework integrates shock staging and hemodynamic stability to guide treatment timing.
- The STABLE checklist aims to standardize triage and decision-making across different heart lesions.

## Abstract

Mechanical complications after acute myocardial infarction (MI)—ventricular septal rupture (VSR), free-wall rupture (FWR), and papillary muscle rupture (PMR)—have become uncommon in the primary percutaneous coronary intervention (PCI) era, yet remain among the most lethal cardiovascular emergencies, with contemporary mortality largely driven by cardiogenic shock and delays to definitive treatment. Although major society documents agree on urgent imaging, early mechanical circulatory support when shock is present, and multidisciplinary decision-making, important transatlantic differences persist, particularly regarding timing of intervention in ventricular septal rupture. This review synthesises current surgical and transcatheter evidence and proposes a unified, physiology-centred framework integrating shock staging, anatomical feasibility, and response to mechanical support. We also introduce STABLE, a structured bedside checklist designed to support consistent daily triage across all three lesions and to align timing decisions with haemodynamic stabilisation rather than centre-specific habit.

## Linked entities

- **Diseases:** acute myocardial infarction (MONDO:0004781), cardiogenic shock (MONDO:0800175)

## Full-text entities

- **Diseases:** Acute Myocardial Infarction (MESH:D009203), PMR (MESH:D012421), Shock (MESH:D012769), cardiovascular emergencies (MESH:D002318), cardiogenic shock (MESH:D012770), VSR (MESH:D018658)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13026845/full.md

## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC13026845/full.md

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Source: https://tomesphere.com/paper/PMC13026845