# Management Protocol for Ballistic and Other High-Energy Avulsive Facial Injuries—An Update for the 21st Century

**Authors:** Thomas Pepper, Michele H. Kim, Dane McMillan, Sarah Cantrell, Angel Scialdone, Angelina Nasthas, Ralph Erdmann, Paul N. Manson, David B. Powers

PMC · DOI: 10.3390/cmtr19010014 · Craniomaxillofacial Trauma & Reconstruction · 2026-03-03

## TL;DR

This paper updates a facial injury management protocol using modern techniques and evidence from recent studies to improve patient outcomes.

## Contribution

The paper introduces an updated four-phase protocol integrating modern surgical and imaging techniques for facial trauma.

## Key findings

- Modern imaging and digital planning improve the accuracy of facial reconstruction.
- Early vascularized tissue transfer reduces complications like contracture and infection.
- The updated protocol emphasizes multidisciplinary collaboration and precision surgery.

## Abstract

High-energy ballistic and avulsive injuries to the face represent some of the most complex challenges in modern reconstructive surgery. Since Robertson and Manson’s 1999 management protocol, extensive military experience and technological advancements have transformed the treatment principles while preserving the core tenets of staged care. This updated review synthesizes evidence from 36 studies published since 2000, encompassing over two decades of global experience in both military and civilian trauma. Advances in damage-control resuscitation, wound decontamination, and early skeletal stabilization have improved survival and functional outcomes. Modern imaging—particularly intraoperative CT and navigation—enables the precise verification of the reduction and removal of retained fragments, while virtual surgical planning and patient-specific implants allow the accurate restoration of facial buttresses. Early vascularized tissue transfer has reduced contracture and infection rates. Adjuncts such as hyperbaric oxygen therapy, permissive hypotension, and advanced hemostatic agents further optimize recovery. The updated four-phase protocol—resuscitation, reconstitution, reconstruction, and rehabilitation—emphasizes early definitive repair, multidisciplinary collaboration, and the integration of digital planning. These refinements extend Robertson and Manson’s foundational principles into the era of precision surgery, achieving superior aesthetic and functional outcomes for patients with devastating facial injuries.

## Full-text entities

- **Genes:** PLG (plasminogen) [NCBI Gene 5340] {aka HAE4}
- **Diseases:** neuropathic pain (MESH:D009437), abdominal pain (MESH:D015746), Infection (MESH:D007239), nausea (MESH:D009325), blast injuries (MESH:D001753), Bleeding (MESH:D006470), Injury (MESH:D014947), facial nerve transection (MESH:D020221), facial fracture (MESH:D005153), Catastrophic Hemorrhage (MESH:D002388), floor-of-mouth loss (MESH:D009059), facial trauma (MESH:D020220), concussion (MESH:D001924), blunt injury (MESH:D014949), war (MESH:D000067398), penetrating injuries to the (MESH:D015807), depression (MESH:D003866), vascular injury (MESH:D057772), hypotension (MESH:D007022), death (MESH:D003643), frontal sinus fracture (MESH:D012852), bone depletion (MESH:D001847), constipation (MESH:D003248), contusion (MESH:D003288), Nerve Injuries (MESH:D000080902), intracranial hemorrhage (MESH:D020300), CSF leak (MESH:D065634), brain injury (MESH:D001930), frontal sinus outflow tract (FSOT) injury (MESH:D000092243), arthritis (MESH:D001168), maxillary defects (MESH:D008439), irritability (MESH:D001523), scars (MESH:D002921), mood change (MESH:D019964), Gunshot wounds (MESH:D014948), pseudocyst (MESH:D010192), mucocele (MESH:D009078), tension pneumothorax (MESH:D011030), maxillofacial injuries (MESH:D008446), wound infection (MESH:D014946), Toxicity (MESH:D064420), psychosocial impairment (MESH:D008607), contracture (MESH:D003286), dural violation (MESH:D020785), avulsion (MESH:D000071562), leak (MESH:D019559), pneumocephalus (MESH:D011007), orbital compartment syndrome (MESH:D003161), ischemia (MESH:D007511), mandibular defects (MESH:D008338), headache (MESH:D006261), volume deficiency (MESH:D007153), craniomaxillofacial injuries (MESH:D000077275), face and neck trauma (MESH:D006258), injury to the neck (MESH:D019838), Lead poisoning (MESH:D007855), Facial Injuries (MESH:D005151), TIC (MESH:D001778), hypertrophic scarring (MESH:D017439), luxation injuries (MESH:D014084)
- **Chemicals:** HemCon (-), ampicillin/sulbactam (MESH:C035444), clindamycin (MESH:D002981), silicone (MESH:D012828), polyethylene (MESH:D020959), Oxygen (MESH:D010100), Alexandrite (MESH:C112654), chitosan (MESH:D048271), zinc (MESH:D015032), kaolin (MESH:D007616), triamcinolone (MESH:D014221), Tranexamic acid (MESH:D014148), ertapenem (MESH:D000077727), PEEK (MESH:C063834), Lead (MESH:D007854), titanium (MESH:D014025), cefazolin (MESH:D002437), graphite (MESH:D006108), iodoform (MESH:C010473), Celox (MESH:C540163), copper (MESH:D003300), moxifloxacin (MESH:D000077266), indocyanine-green (MESH:D007208)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

17 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13026054/full.md

## References

163 references — full list in the complete paper: https://tomesphere.com/paper/PMC13026054/full.md

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Source: https://tomesphere.com/paper/PMC13026054