# Transumbilical Laparoscopic-Assisted (TULA) Surgery for Treating Abdominal Pathologies in Newborns: A Retrospective Single-Center Experience

**Authors:** Giada Loria, Roberta Aurora Aversa, Alessandra Fichera, Agnese Bartolone, Vincenzo Di Benedetto, Maria Grazia Scuderi

PMC · DOI: 10.3390/children13030338 · 2026-02-27

## TL;DR

This study compares transumbilical laparoscopic-assisted surgery with traditional open surgery in newborns, finding similar outcomes and safety.

## Contribution

The paper presents a novel single-center retrospective experience with TULA surgery in neonates and compares it to open surgery.

## Key findings

- TULA surgery had comparable operative times and complication rates to open surgery in neonates.
- No mortality was observed in either the TULA or open surgery groups.
- TULA offers cosmetic benefits and is safe when performed in specialized centers.

## Abstract

Background: Transumbilical laparoscopic-assisted (TULA) surgery is a minimally invasive technique that combines laparoscopic exploration with extracorporeal surgical management, offering potential advantages in neonatal abdominal surgery. However, comparative data with conventional open surgery in neonates remain limited. This study reports our single-center experience with TULA and compares its outcomes with those of a matched cohort of neonates undergoing open surgery. Methods: We performed a retrospective study on neonatal patients (<28 days of life) treated at our Pediatric Surgery Unit between 2015 and 2023. Twenty-five neonates underwent TULA for various intra-abdominal malformations. Each TULA patient was matched in a 1:2 ratio with neonates treated with open surgery based on gestational age, birth weight, and underlying diagnosis, resulting in a matched cohort of 50 patients. Primary outcomes included operative and anesthesia times, conversion rate, postoperative complications, length of hospital stay, and mortality. Results: The TULA cohort included 11 males and 14 females, with a mean gestational age of 37.5 ± 1.9 weeks and a mean birth weight of 2989 ± 675 g. Indications comprised intestinal malrotation, ileal atresia, duodenal stenosis, meconium ileus, and other abdominal pathologies. Mean operative time was comparable between groups (116 ± 37 min in the TULA group vs. 137 ± 65.9 min in the open surgery group; p = 0.52). Conversion from TULA to open surgery occurred in 16% of cases. No significant differences were observed in major postoperative complications or length of hospital stay between groups (p > 0.05). No mortality was reported. Conclusions: TULA represents a safe and effective surgical option for selected neonatal abdominal pathologies, with outcomes comparable to conventional open surgery. When performed in specialized centers with appropriate patient selection and multidisciplinary expertise, TULA offers favorable safety and cosmetic results.

## Linked entities

- **Diseases:** intestinal malrotation (MONDO:0008666), duodenal stenosis (MONDO:0009126), meconium ileus (MONDO:0013843)

## Full-text entities

- **Diseases:** ileal atresia (MESH:D007077), meconium ileus (MESH:D000074270), intra-abdominal malformations (MESH:D000082122), intestinal malrotation (MESH:C562456), duodenal stenosis (MESH:C535720)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13025423/full.md

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Source: https://tomesphere.com/paper/PMC13025423