Antegrade Continence Enema Approaches: Outcomes, Lessons Learned and Overall Burden in a Mixed Urban–Rural Population
Brooklyn Ondrea Campbell, Andrew J. Behrmann, Mahmoud Kutmah, Canon Dew, Tara Kempker, Jessica Peuterbaugh, Venkataraman Ramachandran, Yousef El-Gohary, Ahmed I. Marwan

TL;DR
Two surgical methods for managing chronic constipation had similar effectiveness but differed in hospital stays, readmissions, and costs.
Contribution
The study compares MACE and LC in a mixed urban–rural population, highlighting healthcare utilization and financial burdens.
Findings
MACE had longer hospital stays and higher readmission rates compared to LC.
LC was associated with lower healthcare costs and fewer surgical revisions.
Both procedures achieved comparable continence outcomes after 10 years.
Abstract
What are the main findings? MACE and LC were both effective in managing chronic constipation with similar overall complication rates.MACE was associated with longer hospital stays, higher 30-day readmission rates, more frequent surgical revisions, and higher healthcare costs compared with LC. MACE and LC were both effective in managing chronic constipation with similar overall complication rates. MACE was associated with longer hospital stays, higher 30-day readmission rates, more frequent surgical revisions, and higher healthcare costs compared with LC. What is the implication of the main finding? In mixed urban–rural populations, LC may be preferred due to lower healthcare utilization, reduced financial burden, and fewer postoperative complications. In mixed urban–rural populations, LC may be preferred due to lower healthcare utilization, reduced financial burden, and fewer…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsAppendicitis Diagnosis and Management · Gastrointestinal motility and disorders · Congenital gastrointestinal and neural anomalies
