# Association Between Nursing Diagnoses and Mortality in Patients with Cardiac Disease: A Retrospective Cohort Study

**Authors:** Vanessa Castellanos-Arreola, Ana Cristina Castañeda-Márquez, Raúl Fernando Guerrero-Castañeda, Dulce Milagros Razo-Blanco-Hernández, Luís Ricardo Vázquez-García, Juan Carlos Fernando Sánchez-Velázquez, María del Carmen Velázquez-Núñez, María Yazmin Castañeda-Ramírez, José Ángel Hernández-Mariano

PMC · DOI: 10.3390/clinpract16030049 · 2026-02-26

## TL;DR

This study found that certain nursing diagnoses in cardiac patients are linked to higher or lower in-hospital mortality risks, offering potential for better risk assessment in intensive care.

## Contribution

The study identifies specific nursing diagnoses as independent predictors of mortality in cardiac patients, a novel approach for risk stratification in critical care.

## Key findings

- Diagnoses like fluid volume excess and impaired cardiac output were strongly linked to higher mortality risks.
- Anxiety and impaired psychological comfort were associated with lower mortality risks.
- Nursing diagnoses may serve as clinical markers for predicting outcomes in cardiac intensive care.

## Abstract

Background/Objectives: Cardiovascular diseases represent a considerable burden on healthcare systems. In coronary intensive care units (CICU), nursing staff play a key role in the care of critically ill patients. Nursing diagnoses (NDs) based on the NANDA-I (North American Nursing Diagnosis Association-International) taxonomy enable the identification of human responses to various clinical conditions. However, their association with adverse outcomes, such as in-hospital mortality, remains understudied. Therefore, we evaluated the association between NDs and in-hospital mortality in patients with cardiac disease. Methods: A retrospective cohort study was conducted in a tertiary care hospital. The paper clinical records of 195 patients admitted to the CICU for at least 48 h between January 2023 and March 2025 were reviewed. The association of interest was assessed using Poisson regression models adjusted for confounding variables. Results: Mortality was 24.1%. NDs focusing on cardiac and extracardiac responses, such as fluid volume excess (risk ratio [RR] = 2.67; 95% confidence interval [CI] = 1.23, 5.76), impaired cardiac output (RR = 1.84; 95% CI = 1.50, 2.25), risk of shock (RR = 3.12; 95% CI = 1.91, 5.11), risk for impaired cardiovascular function (RR = 2.01; 95% CI = 1.28, 3.17), and impaired gas exchange (RR = 2.67; 95% CI = 1.64, 4.34) were significant predictors of mortality. In contrast, diagnoses such as anxiety (RR = 0.46; 95% CI = 0.23, 0.91), impaired psychological comfort (RR = 0.31; 95% CI = 0.09, 0.95), and risk of unstable glycemia (RR = 0.46; 95% CI = 0.23, 0.91) were associated with a lower risk of death. Conclusions: NDs are independently associated with in-hospital mortality in critically ill patients with cardiac disease and may represent useful clinical markers for risk stratification in intensive care settings.

## Linked entities

- **Diseases:** cardiac disease (MONDO:0005267)

## Full-text entities

- **Diseases:** impaired gas exchange (MESH:D011007), Pulmonary congestion (MESH:D001261), Decreased cardiac output (MESH:D002303), cardiogenic shock (MESH:D012770), ND (MESH:D001523), pain (MESH:D010146), critically ill (MESH:D016638), CVDs (MESH:D002318), glucose (MESH:D018149), death (MESH:D003643), endothelial injury (MESH:D057772), ventricular dysfunction (MESH:D018754), Cardiac Disease (MESH:D006331), injury to (MESH:D014947), impaired (MESH:D060825), exchange (MESH:D001816), acidosis (MESH:D000138), postoperative (MESH:D019106), stroke (MESH:D020521), arrhythmias (MESH:D001145), Respiratory (MESH:D012131), Anxiety (MESH:D001007), cardiovascular function deterioration (MESH:D018376), altered consciousness (MESH:D003244), valvular heart disease (MESH:D006349), Ischemic heart disease (MESH:D017202), COVID-19 (MESH:D000086382), NANDA-I (MESH:D001759), heart failure (MESH:D006333), NDs (MESH:D065886), Electrolyte disturbances (MESH:D014883), Acute pain (MESH:D059787), cancer (MESH:D009369), neurological injury (MESH:D020196), hypoxemia (MESH:D000860), lactic acidosis (MESH:D000140), organ dysfunction (MESH:D009102), disorders (MESH:D009358), circulatory collapse (MESH:D012769), acute myocardial infarction (MESH:D009203)
- **Chemicals:** potassium (MESH:D011188), oxygen (MESH:D010100), calcium (MESH:D002118), carbon dioxide (MESH:D002245), magnesium (MESH:D008274), sodium (MESH:D012964)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC13025170/full.md

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Source: https://tomesphere.com/paper/PMC13025170