# What Impact Does Lack of Sleep Have on Mental Health?

**Authors:** Haitham Jahrami, Khaled Trabelsi, Seithikurippu R. Pandi-Perumal

PMC · DOI: 10.3390/brainsci16030284 · Brain Sciences · 2026-03-01

## Full-text entities

- **Genes:** MAPT (microtubule associated protein tau) [NCBI Gene 4137] {aka DDPAC, FTD1, FTDP-17, MAPTL, MSTD, MTBT1}, APP (amyloid beta precursor protein) [NCBI Gene 351] {aka AAA, ABETA, ABPP, AD1, APPI, CTFgamma}
- **Diseases:** dementia (MESH:D003704), Lack of Sleep (MESH:D001259), Sleep Deprivation (MESH:D012892), sleep disruption (MESH:D019958), Insomnia (MESH:D007319), AD (MESH:D000544), patterns (MESH:C536309), anxiety (MESH:D001007), injury to (MESH:D014947), Depression (MESH:D003866), Sleep disturbance (MESH:D012893), neuroinflammation (MESH:D000090862), Mental illnesses (MESH:D001523), impaired health-related quality of life (MESH:D000076082), neurodegenerative decline (MESH:D019636)
- **Chemicals:** Omega-3 (MESH:D015525)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC13024322/full.md

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Source: https://tomesphere.com/paper/PMC13024322