# Slow-Oscillation Neurofeedback: A Narrative Review on Clinical Efficacy in Pediatric Settings

**Authors:** Lea Glaubig, Yasmine Azza, Sabrina Beber, Philipp Silbernagl, Isabel Barradas, Angelika Peer, Reinhard Tschiesner

PMC · DOI: 10.3390/bs16030337 · Behavioral Sciences · 2026-02-27

## TL;DR

This review explores the potential of slow-oscillation neurofeedback as a non-drug treatment for mental health and developmental issues in children and teens.

## Contribution

The paper provides a narrative synthesis of clinical evidence for slow-oscillation neurofeedback in pediatric populations.

## Key findings

- SCP neurofeedback shows preliminary efficacy in reducing ADHD symptoms in children who can learn self-regulation.
- Early evidence suggests possible benefits for emotional regulation and behavioral symptoms in ASD and other conditions.
- Methodological inconsistencies limit the clarity of results, and ILF/ISF protocols need further validation.

## Abstract

Slow-oscillation neurofeedback (NF), encompassing slow cortical potential (SCP), infra-low-frequency (ILF), and infra-slow-fluctuation (ISF) protocols, has gained increasing interest as a non-pharmacological intervention in pediatric mental health and neurodevelopmental care. This narrative review synthesizes peer-reviewed literature on the clinical efficacy of slow-oscillation NF in children and adolescents across various conditions, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), epilepsy, tic disorders, and eating-related concerns. SCP NF is the most extensively studied protocol and shows preliminary efficacy in reducing ADHD symptoms, particularly among individuals capable of learning self-regulation. For ASD and other conditions, early evidence from primarily small-scale or uncontrolled studies suggests possible benefits in emotional regulation, impulsivity, and behavioral symptoms, though findings remain mixed and often non-specific. Methodological heterogeneity, including variation in control conditions, training protocols, and outcome measures, limits the comparability of results. ILF and ISF protocols, while promising, are still emerging and require further validation. Overall, slow-oscillation NF appears to offer potential as a personalized therapeutic option for pediatric populations, but robust, well-controlled trials are needed to clarify its clinical utility and optimize its integration into multimodal care.

## Linked entities

- **Diseases:** attention-deficit/hyperactivity disorder (MONDO:0007743), autism spectrum disorder (MONDO:0005258), epilepsy (MONDO:0005027)

## Full-text entities

- **Diseases:** eating-related concerns (MESH:D001068), ADHD (MESH:D001289), ASD (MESH:D000067877), impulsivity (MESH:D007174), tic disorders (MESH:D013981), epilepsy (MESH:D004827)
- **Chemicals:** SCP NF (-)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13024066/full.md

## References

93 references — full list in the complete paper: https://tomesphere.com/paper/PMC13024066/full.md

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Source: https://tomesphere.com/paper/PMC13024066