# Artificial Intelligence-Based Automated Assessment of the Four-Chamber View in Fetal Cardiac Ultrasound Videos

**Authors:** Naoki Teraya, Masaaki Komatsu, Katsuji Takeda, Kanto Shozu, Naoaki Harada, Reina Komatsu, Akira Sakai, Rina Aoyama, Mayumi Kaneko, Ken Asada, Syuzo Kaneko, Kazuki Iwamoto, Akitoshi Nakashima, Ryu Matsuoka, Akihiko Sekizawa, Ryuji Hamamoto

PMC · DOI: 10.3390/bioengineering13030303 · Bioengineering · 2026-03-05

## TL;DR

This paper introduces an AI system that automatically analyzes fetal heart ultrasound videos to detect heart abnormalities, matching the performance of expert doctors.

## Contribution

A novel AI framework for automated four-chamber view extraction and biometric calculation in fetal cardiac ultrasound.

## Key findings

- AI models achieved reliable 4CV extraction and accurate biometric computation.
- Performance was comparable to expert obstetricians in both normal and abnormal cases.
- The system works across different ultrasound systems and reduces missed abnormalities.

## Abstract

The clinical application of artificial intelligence (AI) can provide technical support for examiners and improve obstetric workflow efficiency. In this study, we developed AI models that automatically extract the four-chamber view (4CV) from fetal cardiac ultrasound videos and compute the cardiothoracic area ratio, cardiac axis, and cardiac position for prenatal screening of congenital heart disease. Fetal cardiac ultrasound videos from 301 patients in the second trimester were analyzed. The 4CV was automatically extracted using YOLOv7, followed by image segmentation with UNet 3+ and SegFormer, after which automated parameter calculation and estimation were performed. A clinical comparison study involving 22 obstetricians was conducted to evaluate the screening performance of the AI models. The models demonstrated stable performance in both normal and abnormal cases, including examinations acquired using different ultrasound systems. Furthermore, the AI models achieved screening performance comparable to that of expert obstetricians. These findings indicate that the proposed AI framework enables reliable 4CV extraction and accurate biometric parameter computation. This fully automated approach has the potential to reduce missed abnormalities and improve the consistency of fetal cardiac ultrasound screening.

## Linked entities

- **Diseases:** congenital heart disease (MONDO:0005453)

## Full-text entities

- **Diseases:** congenital heart disease (MESH:D006330)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13023647/full.md

## References

44 references — full list in the complete paper: https://tomesphere.com/paper/PMC13023647/full.md

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Source: https://tomesphere.com/paper/PMC13023647