# Ticks: Biology, Habitat, Threats and Protection Methods

**Authors:** Marlena Szalata, Karolina Wielgus, Mikołaj Danielewski, Andrzej Hnatyszyn, Milena Szalata, Marzena Skrzypczak-Zielińska, Ryszard Słomski

PMC · DOI: 10.3390/biology15060497 · Biology · 2026-03-20

## TL;DR

Ticks are expanding their range due to global warming and transmitting diseases, so understanding their biology and habitats is crucial for prevention and treatment.

## Contribution

The paper highlights the genomic structure of ticks and their unique biological features, which could aid in developing new treatments and vaccines.

## Key findings

- Ticks are active year-round due to global warming, increasing disease transmission risks.
- Tick saliva contains substances that aid in unnoticed blood feeding and may have insecticidal enzymes.
- The tick genome has a high proportion of repetitive genes, which may impact survival and disease transmission.

## Abstract

Recently, increasing attention has been paid to tick bites and the diseases they transmit. Ticks have always accompanied humans and animals, but they can now move rapidly and expand their feeding range. Ticks from the Ixodes family are found in many parts of the world, except for mountainous regions. Ticks transmit Lyme disease, tick-borne encephalitis, anaplasmosis, babesiosis, Powassan infection, and other diseases to humans and animals. They are active from March to November, practically year-round, due to global warming. Hosts include birds, lizards, hedgehogs, goats, roe deer, fallow deer, red deer, foxes, dogs, cats, and humans. The tick genome has already been identified in 10-year surveillance studies, which is crucial for interpreting gene structure. Approximately 70% of the genome consists of repetitive, often mutated, genes. They comprise single copies of the same genus that differ from others to aid arachnid survival. Researchers are examining both genes and applications that facilitate the use and transmission of diseases, potentially helping to develop new treatments and vaccines. Unique aspects of tick biology have been identified. For instance, their saliva contains various bactericidal, analgesic, anticoagulant, and immunosuppressive substances, which may cause ticks to suck blood unnoticed. Ticks also contain enzymes that may possess insecticides.

The most common species of tick in Europe is the castor bean tick (Ixodes ricinus), which is found in forests, parks, and gardens and is active almost all year round. Ticks are among the most important arthropods and vectors of disease, transmitting a wide range of parasites that sometimes lead to the death of infected organisms. The peak incidence of tick-borne diseases occurs between May and September; however, due to global warming, people are increasingly exposed to tick-borne diseases throughout the year. In order to increase the possibility of preventing the transmission of diseases by ticks, it is necessary to become thoroughly familiar with the life cycle of ticks and the environment in which they live. Vaccines are available for some diseases, such as tick-borne encephalitis, while others require a highly specific diagnosis. Another major problem is the long period between the tick bite, which often goes unnoticed or is even ignored by the patient or the doctor, and the development of tick-borne diseases. Increasing attention is being paid to the prevention of tick-borne diseases through prevention of tick bites, quick tick removal, use of repellents, appropriate land management, vaccinations, and the use of plants as natural acaricides.

## Linked entities

- **Diseases:** Lyme disease (MONDO:0019632), tick-borne encephalitis (MONDO:0017572), anaplasmosis (MONDO:0005118), babesiosis (MONDO:0005661)
- **Species:** Ixodes ricinus (taxon 34613), Mus musculus (taxon 10090)

## Full-text entities

- **Diseases:** anaplasmosis (MESH:D000712), melioidosis (MESH:D008554), encephalitis virus (MESH:D018792), chills (MESH:D023341), malaria (MESH:D008288), Disease (MESH:D004194), muscle and joint pain (MESH:D063806), brucellosis (MESH:D002006), death (MESH:D003643), Crimean-Congo hemorrhagic fever (MESH:D006479), bacterial disease (MESH:D001424), rheumatic, musculoskeletal, and neurological diseases (MESH:D009140), Babesiosis (MESH:D001404), Q fever (MESH:D011778), cat scratch disease (MESH:D002372), Bartonellosis (MESH:D001474), Colorado tick fever (MESH:D003121), Lyme (MESH:D008193), autoimmune (MESH:D001327), encephalitis (MESH:D004660), abdominal pain (MESH:D015746), infected (MESH:D007239), Rocky Mountain spotted fever (MESH:D012373), Ehrlichiosis (MESH:D016873), injury to (MESH:D014947), rickettsiae (MESH:D012282), African tick-borne fever (MESH:D012061), leptospirosis (MESH:D007922), coma (MESH:D003128), COVID-19 (MESH:D000086382), respiratory distress (MESH:D012128), headache (MESH:D006261), Powassan infection (MESH:D004675), inflammatory disease of the central nervous system (MESH:D002493), vasculitis (MESH:D014657), plague (MESH:D010930), erythema migrans (MESH:D005929), kidney and liver failure (MESH:D051437), vomiting (MESH:D014839), Francisella tularensis (MESH:D014406), spotted fever rickettsioses (MESH:D000073605), allergic reactions (MESH:D004342), goat fever (MESH:D015511), maculopapular rash (MESH:D005076), bacterial infectious disease (MESH:D003141), jaundice (MESH:D007565), stiff (MESH:C566112), fever (MESH:D005334), diarrhea (MESH:D003967), toxicity (MESH:D064420), tick bites (MESH:D064927), Tick-Borne Diseases (MESH:D017282), arthritis (MESH:D001168), fatigue (MESH:D005221), tick (MESH:D013985)
- **Chemicals:** salt (MESH:D012492), carbon (MESH:D002244), BioRender (-), essential oils (MESH:D009822), water (MESH:D014867), phosphorus (MESH:D010758), nitrogen (MESH:D009584), alcohol (MESH:D000438), iron (MESH:D007501), carbon dioxide (MESH:D002245)
- **Species:** Borreliella afzelii (Borrellia group VS461, species) [taxon 29518], Ixodes lividus (species) [taxon 689458], Erinaceidae (hedgehogs, family) [taxon 9363], Ixodes (genus) [taxon 6944], Lavandula pedunculata (species) [taxon 1343916], Oryctolagus cuniculus (domestic rabbit, species) [taxon 9986], Argas polonicus (species) [taxon 59637], Tabanidae (deerflies, family) [taxon 7205], Azadirachta indica (Indian-lilac, species) [taxon 124943], Ixodes holocyclus (paralysis tick, species) [taxon 65647], Citrullus colocynthis (alhandal, species) [taxon 252529], Francoeuria undulata (species) [taxon 119186], Nepeta cataria (catmint, species) [taxon 39347], Odocoileus virginianus (white-tailed deer, species) [taxon 9874], Rhipicephalus bursa (species) [taxon 67831], Amblyomma varanense (species) [taxon 1274518], Salvia rosmarinus (rosemary, species) [taxon 39367], Rickettsia conorii subsp. raoultii (subspecies) [taxon 369822], Ocimum americanum (American basil, species) [taxon 204141], Ixodes arboricola (species) [taxon 985061], Allium sativum (garlic, species) [taxon 4682], Ixodes simplex (species) [taxon 65648], Clinopodium nepeta (species) [taxon 306383], Rangifer tarandus (caribou, species) [taxon 9870], Soricidae (shrews, family) [taxon 9376], Ornithodoros erraticus (species) [taxon 265619], Ixodes pilosus (bush tick, species) [taxon 44321], Citrus x aurantiifolia (lime, species) [taxon 159033], Rattus norvegicus (brown rat, species) [taxon 10116], Cervus elaphus (red deer, species) [taxon 9860], Haemaphysalis longicornis (longhorned tick, species) [taxon 44386], Rhipicephalus rossicus (species) [taxon 127008], Nepeta racemosa (species) [taxon 54731], Dermacentor albipictus (species) [taxon 60249], Citrus (genus) [taxon 2706], Serpentes (snakes, infraorder) [taxon 8570], Alces alces (elk, species) [taxon 9852], Ixodes hexagonus (hedgehog tick, species) [taxon 34612], Withania somnifera (ashwagandha, species) [taxon 126910], Chamaemelum nobile (species) [taxon 99037], Amblyomma maculatum (Gulf Coast tick, species) [taxon 34609], Artemisia herba-alba (white wormwood, species) [taxon 72329], Coleoptera (beetles, order) [taxon 7041], Mentha suaveolens (apple mint, species) [taxon 38860], Cannabis sativa (species) [taxon 3483], Coxiella burnetii (species) [taxon 777], Haemaphysalis flava (species) [taxon 181088], Amblyomma variegatum (tropical bont tick, species) [taxon 34610], Borrelia miyamotoi (species) [taxon 47466], Microtus arvalis (common vole, species) [taxon 47230], Capra hircus (domestic goat, species) [taxon 9925], Meleagris gallopavo (common turkey, species) [taxon 9103], Hyalomma marginatum (species) [taxon 34627], Ixodes trianguliceps (species) [taxon 347913], Lavandula angustifolia (lavender, species) [taxon 39329], Amblyomma cajennense (Cayenne tick, species) [taxon 34607], Lippia javanica (species) [taxon 925357], Rhipicephalus microplus (cattle tick, species) [taxon 6941], Bos taurus (bovine, species) [taxon 9913], Hyalomma dromedarii (species) [taxon 34626]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13023486/full.md

## References

91 references — full list in the complete paper: https://tomesphere.com/paper/PMC13023486/full.md

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Source: https://tomesphere.com/paper/PMC13023486