# An Unusual Case of Citrobacter koseri Infection During Pregnancy at 27 Weeks: A Case Report and Literature Review

**Authors:** Mario Assenza, Michele Caramia, Jacopo Wabersich

PMC · DOI: 10.1002/ccr3.72342 · Clinical Case Reports · 2026-03-25

## TL;DR

A pregnant woman's asymptomatic Citrobacter koseri infection was successfully treated with antibiotics, preventing harm to mother and baby.

## Contribution

Highlights effective antimicrobial stewardship in managing a rare pregnancy infection.

## Key findings

- Ceftazidime eradicated Citrobacter koseri without maternal or fetal complications.
- Multidisciplinary care prevented neonatal CNS complications and vertical transmission.
- Healthy term delivery occurred with normal Apgar scores.

## Abstract

Early prenatal screening at 26 + 6 weeks detected 
Citrobacter koseri
 vaginal colonization in an asymptomatic high‐risk gravida. Culture‐guided IV ceftazidime (susceptible per CLSI testing) eradicated the pathogen without maternal/fetal compromise. Multidisciplinary management prevented vertical transmission, neonatal CNS complications, and yielded a healthy term delivery (Apgar 9/10). Emphasizes susceptibility‐directed antimicrobial stewardship for optimal outcomes in rare pregnancy infections.

## Linked entities

- **Chemicals:** ceftazidime (PubChem CID 5481173)
- **Species:** Citrobacter koseri (taxon 545)

## Full-text entities

- **Diseases:** pregnancy infections (MESH:D011254), CNS complications (MESH:D002493), Citrobacter koseri Infection (MESH:D007239)
- **Chemicals:** ceftazidime (MESH:D002442)
- **Species:** Citrobacter koseri (species) [taxon 545]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC13022824/full.md

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Source: https://tomesphere.com/paper/PMC13022824