# Expressive pragmatic language in mood and psychotic disorders: a systematic review and meta-analysis

**Authors:** Fiona Meister, Martin Sellier Silva, Gleb Melshin, Chaimaa El Mouslih, Farida Zaher, Roozbeh Sattari, Hsi T. Wei, Neyra Mekideche, Valentina Bambini, Alban Voppel, Lena Palaniyappan

PMC · DOI: 10.1038/s41537-026-00733-2 · Schizophrenia · 2026-02-14

## TL;DR

This study reviews and analyzes how people with severe mental illnesses struggle with using language effectively in social situations, highlighting the need for better assessment and treatment.

## Contribution

The study provides a systematic review and meta-analysis of expressive pragmatic language impairments in adults with severe mental illnesses.

## Key findings

- Significant impairments in Cooperativity, Anaphora, and Cohesion were found in individuals with severe mental illnesses.
- Moderate impairments in Coherence and low impairments in Metaphor were observed.
- No significant moderators influenced the results of the meta-analysis.

## Abstract

Pragmatic language impairments—difficulties using language effectively in social contexts—are common in adults suffering from severe mental illnesses (SMIs) such as schizophrenia spectrum disorders (SSD), major depressive disorder (MDD), and bipolar disorder (BD). These impairments hinder social functioning and recovery but have been explored most widely using comprehension tasks, with pragmatic production being poorly described. We undertook a systematic review and meta-analysis of studies assessing expressive pragmatic language in adults with SMIs versus healthy controls. 18 items were tested, including Coherence, Cohesion, Gricean maxims, figurative language, Prosody, and Turn-Taking. The searches were PRISMA-compliant and were conducted in PubMed and Scopus. 51 studies were included; 28 were meta-analyzed. Results showed significant impairments in Cooperativity, Anaphora and Cohesion, moderate impairments in Coherence, and low impairments in Metaphor. No significant moderator was detected. Our results emphasize the need for standardized pragmatic testing and intervention for language production in clinical settings.

## Linked entities

- **Diseases:** major depressive disorder (MONDO:0002009), bipolar disorder (MONDO:0004985)

## Full-text entities

- **Diseases:** SSD (MESH:D019967), mental illnesses (MESH:D001523), language impairments (MESH:D007806), MDD (MESH:D003865), mood and psychotic disorders (MESH:D000341), BD (MESH:D001714), SMIs (MESH:D045169)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13022284/full.md

## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC13022284/full.md

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Source: https://tomesphere.com/paper/PMC13022284