# OncoVR - Virtual Reality in Oncology for Patient-centered Care: A Systematic Review and Meta-Analysis

**Authors:** Miriam Balzer, Abdelrahman Elsakka, Gijs Luijten, Katrin Schormann, Slobodan Jovic, Monja Gerigk, Laura Mazilescu, Sophia Schmitz, Julius Keyl, Stefan Liszio, Oliver Basu, Beata Maria Goraus, Stefan Kasper, Jens Kleesiek, Behrus Hinrichs-Puladi, Jan Egger

PMC · DOI: 10.1007/s11912-026-01758-7 · Current Oncology Reports · 2026-03-26

## TL;DR

This paper reviews how virtual reality can help cancer patients by improving their well-being and reducing stress during treatment.

## Contribution

The paper systematically reviews and analyzes the role of VR in oncology for patient-centered care.

## Key findings

- VR can reduce stress, anxiety, and nausea in oncology patients.
- VR is well-suited for long-term oncology treatments due to its psychological benefits.
- Ongoing research suggests VR improves patient mental states and treatment experiences.

## Abstract

Due to significant research efforts in the field of virtual reality (VR) and the increasing interest of the gaming industry, technical possibilities have developed rapidly. VR applications have become more extensive in recent years, with devices becoming more convenient and less complex to handle. The purpose of this review was to summarize the current state of research on the use of VR in oncology and to discuss its potential role in patient-centered care.

As a result of technological progress, the benefits of VR have entered the clinical field and are being used in various areas. However, since VR has not yet become part of everyday life, most patients are inexperienced in using these devices. Previous studies have shown that VR applications for oncology patients can improve well-being and reduce stress, anxiety, and nausea during therapy, surgery, and diagnostic procedures. Oncology is particularly well suited for psychological VR applications because cancer can be a potentially traumatic experience with a strong impact on mental health, which in turn can influence therapeutic success. In addition, oncological treatments are usually long-term, making them well suited for studies involving extended VR use.

VR represents a promising supportive tool in oncology, particularly for improving psychological well-being and enhancing patient-centered care. Ongoing research suggests that its use may positively influence both the mental state of patients and the overall treatment experience.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Genes:** NPM1 (nucleophosmin 1) [NCBI Gene 4869] {aka B23, NPM}
- **Diseases:** brain tumor (MESH:D001932), Pain (MESH:D010146), Breast Cancer (MESH:D001943), Chemotherapy (MESH:D000084202), hair loss (MESH:D000505), nausea and vomiting (MESH:D020250), cognitive impairment (MESH:D003072), Fatigue (MESH:D005221), shortness of breathing (MESH:D004417), colorectal cancer (MESH:D015179), Head and Neck Cancer (MESH:D006258), PM (MESH:D008569), acute lymphoblastic leukemia (MESH:D054198), Anxiety (MESH:D001007), Blood Cancer (MESH:D019337), infertility (MESH:D007246), seizures (MESH:D012640), leukaemia (MESH:D015458), skin cancer (MESH:D012878), balance disorders (MESH:D009358), nausea (MESH:D009325), infection (MESH:D007239), neuropathic pain (MESH:D009437), dizziness (MESH:D004244), traumatized (MESH:D014947), AML (MESH:D015470), oesophageal and other gastrointestinal cancer (MESH:D005770), neurological damage (MESH:D020196), CIPN (MESH:D010523), Cancer (MESH:D009369), Depression (MESH:D003866), visual impairment (MESH:D014786), visual field defect (MESH:D005128), death (MESH:D003643)
- **Chemicals:** docetaxel (MESH:D000077143), cortisol (MESH:D006854), morphine (MESH:D009020), Antiemesis (-), tramadol (MESH:D014147), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606], Meleagris gallopavo (common turkey, species) [taxon 9103]

## Full text

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## Figures

12 figures with captions in the complete paper: https://tomesphere.com/paper/PMC13021760/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC13021760/full.md

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Source: https://tomesphere.com/paper/PMC13021760